Spotlight on Glycolysis: A New Target for Cord Blood Expansion

Andrea M. Patterson, Louis M. Pelus

Research output: Contribution to journalShort surveypeer-review

3 Scopus citations

Abstract

Umbilical cord blood (UCB) is a highly valuable but low-quantity source of hematopoietic stem cells (HSCs) for life-saving transplantations. Recently in Nature Medicine, Guo et al. (2018) found that antagonism of a glycolysis-blocking pathway enhances ex vivo expansion of long-term HSCs from human UCB. Umbilical cord blood (UCB) is a highly valuable but low-quantity source of hematopoietic stem cells (HSCs) for life-saving transplantations. Recently in Nature Medicine, Guo et al. (2018) found that antagonism of a glycolysis-blocking pathway enhances ex vivo expansion of long-term HSCs from human UCB.

Original languageEnglish (US)
Pages (from-to)792-793
Number of pages2
JournalCell Stem Cell
Volume22
Issue number6
DOIs
StatePublished - Jun 1 2018

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

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