STAT3 in immune responses and inflammatory bowel diseases

Yuan Fu Xin

Research output: Contribution to journalArticle

50 Scopus citations

Abstract

STAT3 has been known as a mediator for gene expression induced by many important cytokines. Recent studies have suggested that STAT3 has important functions in regulation of both innate and adaptive immunity. Loss of STAT3 in immune cells caused severe inflammation in response to pathogens. This review discusses the recent progress and suggests directions for the future research on this interesting molecule.

Original languageEnglish (US)
Pages (from-to)214-219
Number of pages6
JournalCell Research
Volume16
Issue number2
DOIs
StatePublished - Feb 1 2006

Keywords

  • Autoimmunity
  • Crohn's disease
  • Cytokines
  • Inflammation
  • Innate and adaptive immunity
  • STAT

ASJC Scopus subject areas

  • Cell Biology

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