Stereocontrolled synthesis of (1R,3R,4S)- and (1S,3R,4S)-3,4- diaminocyclopentanols

Yousheng Guan, Mark A. Green, Donald E. Bergstrom

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Cis-syn and cis-anti-3,4-diaminocyclopentanols have been synthesized from cyclopentadiene in eight steps. The key transformations involved construction of benzyl ether protected cis-diazidocyclopentanols, and sequential reduction and hydrogenolysis to the unprotected diaminocyclopentanols.

Original languageEnglish (US)
Pages (from-to)426-428
Number of pages3
Issue number4
StatePublished - Jan 1 1999
Externally publishedYes


  • Debenzylation
  • Diaminocyclopentanol
  • Diazide reduction
  • Stereocontrolled synthesis
  • Vicinal diamine

ASJC Scopus subject areas

  • Organic Chemistry

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