Stereotactic radiosurgery in the treatment of metastatic disease to the brain

Joseph C.T. Chen, Steven O'Day, Donald Morton, Richard Essner, Aron Cohen-Gadol, Dana MacPherson, Steven L. Giannotta, Zbigniew Petrovich, Cheng Yu, Michael L.J. Apuzzo

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

We review 190 consecutive patients with 434 metastatic tumors treated by gamma knife stereotactic radiosurgery, from August 1994 to February 1999. Median actuarial survival for all patients was 34 weeks. Factors correlated with significantly improved survival included controlled systemic disease and nonmelanoma histology. We found that no significant survival benefit could be discerned from adjuvant whole brain radiotherapy in this patient group. Survival was not statistically different for patients initially presenting with 1-4 metastases at initial treatment. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)60-63
Number of pages4
JournalStereotactic and functional neurosurgery
Volume73
Issue number1-4
DOIs
StatePublished - May 2000
Externally publishedYes

Keywords

  • Metastatic brain tumor
  • Metastatic disease
  • Stereotactic radiosurgery

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Stereotactic radiosurgery in the treatment of metastatic disease to the brain'. Together they form a unique fingerprint.

  • Cite this

    Chen, J. C. T., O'Day, S., Morton, D., Essner, R., Cohen-Gadol, A., MacPherson, D., Giannotta, S. L., Petrovich, Z., Yu, C., & Apuzzo, M. L. J. (2000). Stereotactic radiosurgery in the treatment of metastatic disease to the brain. Stereotactic and functional neurosurgery, 73(1-4), 60-63. https://doi.org/10.1159/000029752