Stimulation-induced parkinsonism after posteroventral deep brain stimulation of the globus pallidus internus for craniocervical dystonia

S. Elizabeth Zauber, Nidhi Watson, Cynthia L. Comella, Roy A.E. Bakay, Leo Verhagen Metman

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

The authors report on a patient with craniocervical dystonia who was treated with bilateral GPi stimulation, with excellent improvement in dystonia but at the cost of stimulation-induced, reversible parkinsonism. Stimulation through ventral contacts resulted in maximal relief of craniocervical dystonia but induced considerable hypophonia, bradykinesia, rigidity, freezing, and impaired postural reflexes. Stimulation through dorsal contacts alleviated parkinsonism, but resulted in the return of dystonia. No stimulation parameters could alleviate the dystonia without inducing parkinsonism over the course of his 4-year follow-up.

Original languageEnglish (US)
Pages (from-to)229-233
Number of pages5
JournalJournal of neurosurgery
Volume110
Issue number2
DOIs
StatePublished - Feb 1 2009
Externally publishedYes

Keywords

  • Deep brain stimulation
  • Dystonia
  • Globus pallidus internus
  • Parkinsonism

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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