Strategic plan for pediatric respiratory diseases research

An NHLBI working group report

Mario Castro, Maria I. Ramirez, James E. Gern, Garry Cutting, Greg Redding, James S. Hagood, Jeffrey Whitsett, Steve Abman, J. Usha Raj, Robyn Barst, Gregory J. Kato, David Gozal, Gabriel G. Haddad, Nanduri R. Prabhakar, Estelle Gauda, Fernando D. Martinez, Robert Tepper, Robert E. Wood, Frank Accurso, W. Gerald Teague & 4 others Jose Venegas, F. Sessions Cole, Rosalind J. Wright, Carol J. Blaisdell

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The Division of Lung Diseases of the National Heart, Lung, and Blood Institute (NHLBI) recently held a workshop to identify gaps in our understanding and treatment of childhood lung diseases and to define strategies to enhance translational research in this field. Leading experts with diverse experience in both laboratory and patient-oriented research reviewed selected areas of pediatric lung diseases, including perinatal programming and epigenetic influences; mechanisms of lung injury, repair, and regeneration; pulmonary vascular disease; sleep and control of breathing; and the application of novel translational methods to enhance personalized medicine. This report summarizes the proceedings of this workshop and provides recommendations for emphasis on targeted areas for future investigation. The priority areas identified for research in pediatric pulmonary diseases included: (1) epigenetic and environmental influences on lung development that program pediatric lung diseases; (2) injury, regeneration, and repair in the developing lung; (3) pulmonary vascular disease in children; (4) development and adaptation of ventilatory responses to postnatal life; (5) nonatopic wheezing: aberrant large airway development or injury?; (6) strategies to improve assessment, diagnosis, and treatment of pediatric respiratory diseases; and (7) predictive and personalized medicine for children.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalProceedings of the American Thoracic Society
Volume6
Issue number1
DOIs
StatePublished - Jan 2009

Fingerprint

National Heart, Lung, and Blood Institute (U.S.)
Lung Diseases
Pediatrics
Research
Precision Medicine
Vascular Diseases
Epigenomics
Regeneration
Education
Lung
Translational Medical Research
Respiratory Sounds
Wounds and Injuries
Lung Injury
Sleep
Respiration
Therapeutics

Keywords

  • Epigenetics
  • Lung injury
  • Pulmonary vascular disease
  • Ventilator control
  • Wheezing

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Castro, M., Ramirez, M. I., Gern, J. E., Cutting, G., Redding, G., Hagood, J. S., ... Blaisdell, C. J. (2009). Strategic plan for pediatric respiratory diseases research: An NHLBI working group report. Proceedings of the American Thoracic Society, 6(1), 1-10. https://doi.org/10.1513/pats.200810-116CB

Strategic plan for pediatric respiratory diseases research : An NHLBI working group report. / Castro, Mario; Ramirez, Maria I.; Gern, James E.; Cutting, Garry; Redding, Greg; Hagood, James S.; Whitsett, Jeffrey; Abman, Steve; Raj, J. Usha; Barst, Robyn; Kato, Gregory J.; Gozal, David; Haddad, Gabriel G.; Prabhakar, Nanduri R.; Gauda, Estelle; Martinez, Fernando D.; Tepper, Robert; Wood, Robert E.; Accurso, Frank; Teague, W. Gerald; Venegas, Jose; Cole, F. Sessions; Wright, Rosalind J.; Blaisdell, Carol J.

In: Proceedings of the American Thoracic Society, Vol. 6, No. 1, 01.2009, p. 1-10.

Research output: Contribution to journalArticle

Castro, M, Ramirez, MI, Gern, JE, Cutting, G, Redding, G, Hagood, JS, Whitsett, J, Abman, S, Raj, JU, Barst, R, Kato, GJ, Gozal, D, Haddad, GG, Prabhakar, NR, Gauda, E, Martinez, FD, Tepper, R, Wood, RE, Accurso, F, Teague, WG, Venegas, J, Cole, FS, Wright, RJ & Blaisdell, CJ 2009, 'Strategic plan for pediatric respiratory diseases research: An NHLBI working group report', Proceedings of the American Thoracic Society, vol. 6, no. 1, pp. 1-10. https://doi.org/10.1513/pats.200810-116CB
Castro, Mario ; Ramirez, Maria I. ; Gern, James E. ; Cutting, Garry ; Redding, Greg ; Hagood, James S. ; Whitsett, Jeffrey ; Abman, Steve ; Raj, J. Usha ; Barst, Robyn ; Kato, Gregory J. ; Gozal, David ; Haddad, Gabriel G. ; Prabhakar, Nanduri R. ; Gauda, Estelle ; Martinez, Fernando D. ; Tepper, Robert ; Wood, Robert E. ; Accurso, Frank ; Teague, W. Gerald ; Venegas, Jose ; Cole, F. Sessions ; Wright, Rosalind J. ; Blaisdell, Carol J. / Strategic plan for pediatric respiratory diseases research : An NHLBI working group report. In: Proceedings of the American Thoracic Society. 2009 ; Vol. 6, No. 1. pp. 1-10.
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