Strategic plan for pediatric respiratory diseases research: An NHLBI working group report

Mario Castro, Maria I. Ramirez, James E. Gern, Garry Cutting, Greg Redding, James S. Hagood, Jeffrey Whitsett, Steve Abman, J. Usha Raj, Robyn Barst, Gregory J. Kato, David Gozal, Gabriel G. Haddad, Nanduri R. Prabhakar, Estelle Gauda, Fernando D. Martinez, Robert Tepper, Robert E. Wood, Frank Accurso, W. Gerald TeagueJose Venegas, F. Sessions Cole, Rosalind J. Wright, Carol J. Blaisdell

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The Division of Lung Diseases of the National Heart, Lung and Blood Institute (NHLBI) recently held a workshop to identify gaps in our understanding and treatment of childhood lung diseases and to define strategies to enhance translational research in this field. Leading experts with diverse experience in both laboratory and patient-oriented research reviewed selected areas of pediatric lung diseases, including perinatal programming and epigenetic influences; mechanisms of lung injury, repair, and regeneration; pulmonary vascular disease (PVD); sleep and control of breathing; and the application of novel translational methods to enhance personalized medicine. This report summarizes the proceedings of this workshop and provides recommendations for emphasis on targeted areas for future investigation. The priority areas identified for research in pediatric pulmonary diseases included: (1) epigenetic and environmental influences on lung development that program pediatric lung diseases, (2) injury, regeneration, and repair in the developing lung, (3) PVD in children, (4) development and adaptation of ventilatory responses to postnatal life, (5) nonatopic wheezing: aberrant large airway development or injury? (6) strategies to improve assessment, diagnosis, and treatment of pediatric respiratory diseases, and (7) predictive and personalized medicine for children.

Original languageEnglish
Pages (from-to)2-13
Number of pages12
JournalPediatric Pulmonology
Volume44
Issue number1
DOIs
StatePublished - Jan 2009

Fingerprint

National Heart, Lung, and Blood Institute (U.S.)
Lung Diseases
Pediatrics
Research
Precision Medicine
Vascular Diseases
Epigenomics
Regeneration
Education
Lung
Translational Medical Research
Respiratory Sounds
Wounds and Injuries
Lung Injury
Child Development
Sleep
Respiration
Therapeutics

Keywords

  • Epigenetics
  • Lung disease
  • Pediatric
  • Respiratory

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Cite this

Castro, M., Ramirez, M. I., Gern, J. E., Cutting, G., Redding, G., Hagood, J. S., ... Blaisdell, C. J. (2009). Strategic plan for pediatric respiratory diseases research: An NHLBI working group report. Pediatric Pulmonology, 44(1), 2-13. https://doi.org/10.1002/ppul.20973

Strategic plan for pediatric respiratory diseases research : An NHLBI working group report. / Castro, Mario; Ramirez, Maria I.; Gern, James E.; Cutting, Garry; Redding, Greg; Hagood, James S.; Whitsett, Jeffrey; Abman, Steve; Usha Raj, J.; Barst, Robyn; Kato, Gregory J.; Gozal, David; Haddad, Gabriel G.; Prabhakar, Nanduri R.; Gauda, Estelle; Martinez, Fernando D.; Tepper, Robert; Wood, Robert E.; Accurso, Frank; Gerald Teague, W.; Venegas, Jose; Sessions Cole, F.; Wright, Rosalind J.; Blaisdell, Carol J.

In: Pediatric Pulmonology, Vol. 44, No. 1, 01.2009, p. 2-13.

Research output: Contribution to journalArticle

Castro, M, Ramirez, MI, Gern, JE, Cutting, G, Redding, G, Hagood, JS, Whitsett, J, Abman, S, Usha Raj, J, Barst, R, Kato, GJ, Gozal, D, Haddad, GG, Prabhakar, NR, Gauda, E, Martinez, FD, Tepper, R, Wood, RE, Accurso, F, Gerald Teague, W, Venegas, J, Sessions Cole, F, Wright, RJ & Blaisdell, CJ 2009, 'Strategic plan for pediatric respiratory diseases research: An NHLBI working group report', Pediatric Pulmonology, vol. 44, no. 1, pp. 2-13. https://doi.org/10.1002/ppul.20973
Castro, Mario ; Ramirez, Maria I. ; Gern, James E. ; Cutting, Garry ; Redding, Greg ; Hagood, James S. ; Whitsett, Jeffrey ; Abman, Steve ; Usha Raj, J. ; Barst, Robyn ; Kato, Gregory J. ; Gozal, David ; Haddad, Gabriel G. ; Prabhakar, Nanduri R. ; Gauda, Estelle ; Martinez, Fernando D. ; Tepper, Robert ; Wood, Robert E. ; Accurso, Frank ; Gerald Teague, W. ; Venegas, Jose ; Sessions Cole, F. ; Wright, Rosalind J. ; Blaisdell, Carol J. / Strategic plan for pediatric respiratory diseases research : An NHLBI working group report. In: Pediatric Pulmonology. 2009 ; Vol. 44, No. 1. pp. 2-13.
@article{f891fa1cda6241e3a4e678b7007a03ce,
title = "Strategic plan for pediatric respiratory diseases research: An NHLBI working group report",
abstract = "The Division of Lung Diseases of the National Heart, Lung and Blood Institute (NHLBI) recently held a workshop to identify gaps in our understanding and treatment of childhood lung diseases and to define strategies to enhance translational research in this field. Leading experts with diverse experience in both laboratory and patient-oriented research reviewed selected areas of pediatric lung diseases, including perinatal programming and epigenetic influences; mechanisms of lung injury, repair, and regeneration; pulmonary vascular disease (PVD); sleep and control of breathing; and the application of novel translational methods to enhance personalized medicine. This report summarizes the proceedings of this workshop and provides recommendations for emphasis on targeted areas for future investigation. The priority areas identified for research in pediatric pulmonary diseases included: (1) epigenetic and environmental influences on lung development that program pediatric lung diseases, (2) injury, regeneration, and repair in the developing lung, (3) PVD in children, (4) development and adaptation of ventilatory responses to postnatal life, (5) nonatopic wheezing: aberrant large airway development or injury? (6) strategies to improve assessment, diagnosis, and treatment of pediatric respiratory diseases, and (7) predictive and personalized medicine for children.",
keywords = "Epigenetics, Lung disease, Pediatric, Respiratory",
author = "Mario Castro and Ramirez, {Maria I.} and Gern, {James E.} and Garry Cutting and Greg Redding and Hagood, {James S.} and Jeffrey Whitsett and Steve Abman and {Usha Raj}, J. and Robyn Barst and Kato, {Gregory J.} and David Gozal and Haddad, {Gabriel G.} and Prabhakar, {Nanduri R.} and Estelle Gauda and Martinez, {Fernando D.} and Robert Tepper and Wood, {Robert E.} and Frank Accurso and {Gerald Teague}, W. and Jose Venegas and {Sessions Cole}, F. and Wright, {Rosalind J.} and Blaisdell, {Carol J.}",
year = "2009",
month = "1",
doi = "10.1002/ppul.20973",
language = "English",
volume = "44",
pages = "2--13",
journal = "Pediatric Pulmonology",
issn = "8755-6863",
publisher = "Wiley-Liss Inc.",
number = "1",

}

TY - JOUR

T1 - Strategic plan for pediatric respiratory diseases research

T2 - An NHLBI working group report

AU - Castro, Mario

AU - Ramirez, Maria I.

AU - Gern, James E.

AU - Cutting, Garry

AU - Redding, Greg

AU - Hagood, James S.

AU - Whitsett, Jeffrey

AU - Abman, Steve

AU - Usha Raj, J.

AU - Barst, Robyn

AU - Kato, Gregory J.

AU - Gozal, David

AU - Haddad, Gabriel G.

AU - Prabhakar, Nanduri R.

AU - Gauda, Estelle

AU - Martinez, Fernando D.

AU - Tepper, Robert

AU - Wood, Robert E.

AU - Accurso, Frank

AU - Gerald Teague, W.

AU - Venegas, Jose

AU - Sessions Cole, F.

AU - Wright, Rosalind J.

AU - Blaisdell, Carol J.

PY - 2009/1

Y1 - 2009/1

N2 - The Division of Lung Diseases of the National Heart, Lung and Blood Institute (NHLBI) recently held a workshop to identify gaps in our understanding and treatment of childhood lung diseases and to define strategies to enhance translational research in this field. Leading experts with diverse experience in both laboratory and patient-oriented research reviewed selected areas of pediatric lung diseases, including perinatal programming and epigenetic influences; mechanisms of lung injury, repair, and regeneration; pulmonary vascular disease (PVD); sleep and control of breathing; and the application of novel translational methods to enhance personalized medicine. This report summarizes the proceedings of this workshop and provides recommendations for emphasis on targeted areas for future investigation. The priority areas identified for research in pediatric pulmonary diseases included: (1) epigenetic and environmental influences on lung development that program pediatric lung diseases, (2) injury, regeneration, and repair in the developing lung, (3) PVD in children, (4) development and adaptation of ventilatory responses to postnatal life, (5) nonatopic wheezing: aberrant large airway development or injury? (6) strategies to improve assessment, diagnosis, and treatment of pediatric respiratory diseases, and (7) predictive and personalized medicine for children.

AB - The Division of Lung Diseases of the National Heart, Lung and Blood Institute (NHLBI) recently held a workshop to identify gaps in our understanding and treatment of childhood lung diseases and to define strategies to enhance translational research in this field. Leading experts with diverse experience in both laboratory and patient-oriented research reviewed selected areas of pediatric lung diseases, including perinatal programming and epigenetic influences; mechanisms of lung injury, repair, and regeneration; pulmonary vascular disease (PVD); sleep and control of breathing; and the application of novel translational methods to enhance personalized medicine. This report summarizes the proceedings of this workshop and provides recommendations for emphasis on targeted areas for future investigation. The priority areas identified for research in pediatric pulmonary diseases included: (1) epigenetic and environmental influences on lung development that program pediatric lung diseases, (2) injury, regeneration, and repair in the developing lung, (3) PVD in children, (4) development and adaptation of ventilatory responses to postnatal life, (5) nonatopic wheezing: aberrant large airway development or injury? (6) strategies to improve assessment, diagnosis, and treatment of pediatric respiratory diseases, and (7) predictive and personalized medicine for children.

KW - Epigenetics

KW - Lung disease

KW - Pediatric

KW - Respiratory

UR - http://www.scopus.com/inward/record.url?scp=58149523152&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58149523152&partnerID=8YFLogxK

U2 - 10.1002/ppul.20973

DO - 10.1002/ppul.20973

M3 - Article

C2 - 19086051

AN - SCOPUS:58149523152

VL - 44

SP - 2

EP - 13

JO - Pediatric Pulmonology

JF - Pediatric Pulmonology

SN - 8755-6863

IS - 1

ER -