Stroke volume calculated from the mitral valve echogram in patients with and without ventricular dyssynergy

S. Rasmussen, B. C. Corya, Harvey Feigenbaum, M. J. Black, D. E. Lovelace, J. F. Phillips, R. J. Noble, S. B. Knoebel

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A formula was derived for calculating mitral valve stroke volume (MVSV) using the rate of mitral valve (MV) opening (DE slope on the MV echogram), the vertical distance between the mitral leaflet echoes early in diastole (EE), the electrocardiographic PR interval and heart rate. The formula was tested prospectively on 80 consecutive patients from whom 95 simultaneous MV echograms and either thermodilution (45) or Fick (50) cardiac outputs were obtained. Sixteen patients were normal; 54 had coronary artery disease; three had cardiomyopathy; and seven had nonrheumatic mitral regurgitation (MR). Linear regression for stroke volume was r 0.90, SEE ±6, and for cardiac output r 0.83, SEE ±0.5 liter for the 73 patients without MR. The presence or absence of ventricular dyssynergy did not alter statistical findings. MVSV consistently overestimated forward stroke volume for the seven patients with MR. This study shows that the MV echogram provides an accurate, widely applicable method for calculating MVSV.

Original languageEnglish
Pages (from-to)125-133
Number of pages9
JournalCirculation
Volume58
Issue number1
StatePublished - 1978

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Mitral Valve
Stroke Volume
Mitral Valve Insufficiency
Cardiac Output
Thermodilution
Diastole
Cardiomyopathies
Coronary Artery Disease
Linear Models
Heart Rate

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Rasmussen, S., Corya, B. C., Feigenbaum, H., Black, M. J., Lovelace, D. E., Phillips, J. F., ... Knoebel, S. B. (1978). Stroke volume calculated from the mitral valve echogram in patients with and without ventricular dyssynergy. Circulation, 58(1), 125-133.

Stroke volume calculated from the mitral valve echogram in patients with and without ventricular dyssynergy. / Rasmussen, S.; Corya, B. C.; Feigenbaum, Harvey; Black, M. J.; Lovelace, D. E.; Phillips, J. F.; Noble, R. J.; Knoebel, S. B.

In: Circulation, Vol. 58, No. 1, 1978, p. 125-133.

Research output: Contribution to journalArticle

Rasmussen, S, Corya, BC, Feigenbaum, H, Black, MJ, Lovelace, DE, Phillips, JF, Noble, RJ & Knoebel, SB 1978, 'Stroke volume calculated from the mitral valve echogram in patients with and without ventricular dyssynergy', Circulation, vol. 58, no. 1, pp. 125-133.
Rasmussen S, Corya BC, Feigenbaum H, Black MJ, Lovelace DE, Phillips JF et al. Stroke volume calculated from the mitral valve echogram in patients with and without ventricular dyssynergy. Circulation. 1978;58(1):125-133.
Rasmussen, S. ; Corya, B. C. ; Feigenbaum, Harvey ; Black, M. J. ; Lovelace, D. E. ; Phillips, J. F. ; Noble, R. J. ; Knoebel, S. B. / Stroke volume calculated from the mitral valve echogram in patients with and without ventricular dyssynergy. In: Circulation. 1978 ; Vol. 58, No. 1. pp. 125-133.
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AU - Rasmussen, S.

AU - Corya, B. C.

AU - Feigenbaum, Harvey

AU - Black, M. J.

AU - Lovelace, D. E.

AU - Phillips, J. F.

AU - Noble, R. J.

AU - Knoebel, S. B.

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N2 - A formula was derived for calculating mitral valve stroke volume (MVSV) using the rate of mitral valve (MV) opening (DE slope on the MV echogram), the vertical distance between the mitral leaflet echoes early in diastole (EE), the electrocardiographic PR interval and heart rate. The formula was tested prospectively on 80 consecutive patients from whom 95 simultaneous MV echograms and either thermodilution (45) or Fick (50) cardiac outputs were obtained. Sixteen patients were normal; 54 had coronary artery disease; three had cardiomyopathy; and seven had nonrheumatic mitral regurgitation (MR). Linear regression for stroke volume was r 0.90, SEE ±6, and for cardiac output r 0.83, SEE ±0.5 liter for the 73 patients without MR. The presence or absence of ventricular dyssynergy did not alter statistical findings. MVSV consistently overestimated forward stroke volume for the seven patients with MR. This study shows that the MV echogram provides an accurate, widely applicable method for calculating MVSV.

AB - A formula was derived for calculating mitral valve stroke volume (MVSV) using the rate of mitral valve (MV) opening (DE slope on the MV echogram), the vertical distance between the mitral leaflet echoes early in diastole (EE), the electrocardiographic PR interval and heart rate. The formula was tested prospectively on 80 consecutive patients from whom 95 simultaneous MV echograms and either thermodilution (45) or Fick (50) cardiac outputs were obtained. Sixteen patients were normal; 54 had coronary artery disease; three had cardiomyopathy; and seven had nonrheumatic mitral regurgitation (MR). Linear regression for stroke volume was r 0.90, SEE ±6, and for cardiac output r 0.83, SEE ±0.5 liter for the 73 patients without MR. The presence or absence of ventricular dyssynergy did not alter statistical findings. MVSV consistently overestimated forward stroke volume for the seven patients with MR. This study shows that the MV echogram provides an accurate, widely applicable method for calculating MVSV.

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