Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development

M. I. Klein, S. Duarte, J. Xiao, S. Mitra, T. H. Foster, H. Koo

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

The interaction of sucrose and starch with bacterial glucosyltransferases and human salivary amylase may enhance the pathogenic potential of Streptococcus mutatis within biofilms by influencing the structural organization of the extracellular matrix and modulating the expression of genes involved in exopolysaccharide synthesis and specific sugar transport and two-component systems.

Original languageEnglish (US)
Pages (from-to)837-841
Number of pages5
JournalApplied and Environmental Microbiology
Volume75
Issue number3
DOIs
StatePublished - Feb 1 2009

Fingerprint

Glucosyltransferases
Streptococcus mutans
glucosyltransferases
exopolysaccharides
Streptococcus
Amylases
Biofilms
sucrose
extracellular matrix
amylases
starch
Starch
biofilm
Extracellular Matrix
Sucrose
sugar
pathogenicity
sugars
Gene Expression
gene expression

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

Cite this

Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development. / Klein, M. I.; Duarte, S.; Xiao, J.; Mitra, S.; Foster, T. H.; Koo, H.

In: Applied and Environmental Microbiology, Vol. 75, No. 3, 01.02.2009, p. 837-841.

Research output: Contribution to journalArticle

Klein, M. I. ; Duarte, S. ; Xiao, J. ; Mitra, S. ; Foster, T. H. ; Koo, H. / Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development. In: Applied and Environmental Microbiology. 2009 ; Vol. 75, No. 3. pp. 837-841.
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