Structural and molecular basis of the role of starch and sucrose in streptococcus mutans biofilm development

M. I. Klein, S. Duarte, J. Xiao, S. Mitra, T. H. Foster, H. Koo

Research output: Contribution to journalArticle

79 Scopus citations


The interaction of sucrose and starch with bacterial glucosyltransferases and human salivary amylase may enhance the pathogenic potential of Streptococcus mutatis within biofilms by influencing the structural organization of the extracellular matrix and modulating the expression of genes involved in exopolysaccharide synthesis and specific sugar transport and two-component systems.

Original languageEnglish (US)
Pages (from-to)837-841
Number of pages5
JournalApplied and environmental microbiology
Issue number3
StatePublished - Feb 1 2009


ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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