Structural characterization of a metal-based perfusion tracer: Copper(II) pyruvaldehyde bis (N4-methylthiosemicarbazone)

E. John, P. E. Fanwick, A. T. McKenzie, J. G. Stowell, Mark Green

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Copper(II) pyruvaldehyde bis(N4-methylthiosemicarbazone), Cu(PTSM), has been obtained as a dark red crystalline solid from EtOH-DMSO solvent mixture and structurally characterized by x-ray crystallography. The molecule possesses the expected pseudo-square planar N2S2 metal coordination sphere; however, the copper center also interacts through its axial coordination site with the sulfur atom of an adjacent Cu(PTSM) molecule in the crystal lattice. The structure of this compound is compared with the structures of other metal complexes that have been proposed in the nuclear medicine literature as perfusion tracers.

Original languageEnglish (US)
JournalInternational Journal of Radiation Applications and Instrumentation.
Volume16
Issue number8
DOIs
StatePublished - 1989
Externally publishedYes

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Pyruvaldehyde
Copper
Medicine in Literature
Perfusion
Metals
Crystallography
Nuclear Medicine
Coordination Complexes
Dimethyl Sulfoxide
Sulfur
X-Rays
copper pyruvaldehyde bis(N(4)-methylthiosemicarbazone) complex

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Structural characterization of a metal-based perfusion tracer : Copper(II) pyruvaldehyde bis (N4-methylthiosemicarbazone). / John, E.; Fanwick, P. E.; McKenzie, A. T.; Stowell, J. G.; Green, Mark.

In: International Journal of Radiation Applications and Instrumentation., Vol. 16, No. 8, 1989.

Research output: Contribution to journalArticle

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