Structural characterization of a metal-based perfusion tracer: Copper(II) pyruvaldehyde bis (N4-methylthiosemicarbazone)

Elizabeth John, Phillip E. Fanwick, Ann T. Mckenzie, Joseph G. Stowell, Mark A. Green

Research output: Contribution to journalArticle

28 Scopus citations


Copper(II) pyruvaldehyde bis(N4-methylthiosemicarbazone), Cu(PTSM), has been obtained as a dark red crystalline solid from EtOH-DMSO solvent mixture and structurally characterized by x-ray crystallography. The molecule possesses the expected pseudo-square planar N2S2 metal coordination sphere; however, the copper center also interacts through its axial coordination site with the sulfur atom of an adjacent Cu(PTSM) molecule in the crystal lattice. The structure of this compound is compared with the structures of other metal complexes that have been proposed in the nuclear medicine literature as perfusion tracers.

Original languageEnglish (US)
Pages (from-to)791-795,797
JournalInternational Journal of Radiation Applications and Instrumentation.
Issue number8
StatePublished - 1989


ASJC Scopus subject areas

  • Medicine(all)

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