Structure of isometric viruses containing nonidentical polypeptide chains

Research output: Contribution to journalArticle

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Abstract

The theory of Caspar and Klug (1962) for the structure of isometric viruses has been generalized to the case in which the identical repeating unit is composed of n nonidentical polypeptide chains. This modified theory accounts for the structure of picornaviruses, the lambda phage head, cowpea mosaic virus, and phiX174, while at the same time conserving the principle of having identical subunits in identical environments. Furthermore, the modified theory suggests amending the triangulation number to T[n] for capsids with n nonidentical polypeptide chains as the repeating unit.

Original languageEnglish (US)
Pages (from-to)878-885
Number of pages8
JournalJournal of virology
Volume14
Issue number4
StatePublished - Dec 1 1974

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Viral Structures
polypeptides
Cowpea mosaic virus
Comovirus
Picornaviridae
Bacteriophage lambda
viruses
Peptides
capsid
Capsid
bacteriophages

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Cite this

Structure of isometric viruses containing nonidentical polypeptide chains. / Dunker, A. K.

In: Journal of virology, Vol. 14, No. 4, 01.12.1974, p. 878-885.

Research output: Contribution to journalArticle

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