Successful treatment of disseminated Fusarium infection after autologous bone marrow transplantation for acute myeloid leukemia

M. J. Robertson, M. A. Socinski, R. J. Soiffer, R. W. Finberg, C. Wilson, K. C. Anderson, L. Bosserman, D. N. Sang, I. F. Salkin, J. Ritz

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Disseminated Fusarium is a rare but life-threatening infection of severely immunocompromised patients. A fatal outcome has been described in all reported cases of Fusarium infection occurring after bone marrow transplantation. We describe a patient who developed disseminated Fusarium infection with a secondary fungal endophthalmitis after an autologous bone marrow transplant for acute myeloid leukemia. This infection was successfully eradicated after neutrophil recovery by prolonged systemic administration of amphotericin B as well as aggressive local therapy including enucleation of the affected eye. The patient remains free of both leukaemia and fungal disease more than 4 years after transplant.

Original languageEnglish (US)
Pages (from-to)143-145
Number of pages3
JournalBone marrow transplantation
Volume8
Issue number2
StatePublished - 1991

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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