Successful treatment of disseminated Fusarium infection after autologous bone marrow transplantation for acute myeloid leukemia

Michael Robertson, M. A. Socinski, R. J. Soiffer, R. W. Finberg, C. Wilson, K. C. Anderson, L. Bosserman, D. N. Sang, I. F. Salkin, J. Ritz

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Disseminated Fusarium is a rare but life-threatening infection of severely immunocompromised patients. A fatal outcome has been described in all reported cases of Fusarium infection occurring after bone marrow transplantation. We describe a patient who developed disseminated Fusarium infection with a secondary fungal endophthalmitis after an autologous bone marrow transplant for acute myeloid leukemia. This infection was successfully eradicated after neutrophil recovery by prolonged systemic administration of amphotericin B as well as aggressive local therapy including enucleation of the affected eye. The patient remains free of both leukaemia and fungal disease more than 4 years after transplant.

Original languageEnglish (US)
Pages (from-to)143-145
Number of pages3
JournalBone Marrow Transplantation
Volume8
Issue number2
StatePublished - 1991
Externally publishedYes

Fingerprint

Fusariosis
Autologous Transplantation
Bone Marrow Transplantation
Acute Myeloid Leukemia
Eye Enucleation
Transplants
Endophthalmitis
Fatal Outcome
Mycoses
Fusarium
Immunocompromised Host
Amphotericin B
Infection
Leukemia
Neutrophils
Bone Marrow
Therapeutics

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Robertson, M., Socinski, M. A., Soiffer, R. J., Finberg, R. W., Wilson, C., Anderson, K. C., ... Ritz, J. (1991). Successful treatment of disseminated Fusarium infection after autologous bone marrow transplantation for acute myeloid leukemia. Bone Marrow Transplantation, 8(2), 143-145.

Successful treatment of disseminated Fusarium infection after autologous bone marrow transplantation for acute myeloid leukemia. / Robertson, Michael; Socinski, M. A.; Soiffer, R. J.; Finberg, R. W.; Wilson, C.; Anderson, K. C.; Bosserman, L.; Sang, D. N.; Salkin, I. F.; Ritz, J.

In: Bone Marrow Transplantation, Vol. 8, No. 2, 1991, p. 143-145.

Research output: Contribution to journalArticle

Robertson, M, Socinski, MA, Soiffer, RJ, Finberg, RW, Wilson, C, Anderson, KC, Bosserman, L, Sang, DN, Salkin, IF & Ritz, J 1991, 'Successful treatment of disseminated Fusarium infection after autologous bone marrow transplantation for acute myeloid leukemia', Bone Marrow Transplantation, vol. 8, no. 2, pp. 143-145.
Robertson, Michael ; Socinski, M. A. ; Soiffer, R. J. ; Finberg, R. W. ; Wilson, C. ; Anderson, K. C. ; Bosserman, L. ; Sang, D. N. ; Salkin, I. F. ; Ritz, J. / Successful treatment of disseminated Fusarium infection after autologous bone marrow transplantation for acute myeloid leukemia. In: Bone Marrow Transplantation. 1991 ; Vol. 8, No. 2. pp. 143-145.
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