Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation

D. W. Branch, L. Ducat, A. Fantel, W. C. Low, Feng Zhou, D. H. Dayton, T. J. Gill

Research output: Contribution to journalArticle

Abstract

Objective. - To assess the potential availability and utility of fetal tissues obtained from spontaneous abortions and from ectopic pregnancies for human transplantation therapy. Design. - Tissue collection and analysis by personnel skilled in tissue banking. Setting. - Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health. Patients. - All women entering obstetric clinics during 1993 who consented to participate in the study. Interventions. - None. Main Outcome Measures. - Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria. Results. - From 22 235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5%) were potentially useful for human transplantation therapy. Conclusion. - Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.

Original languageEnglish (US)
Pages (from-to)66-68
Number of pages3
JournalJournal of the American Medical Association
Volume273
Issue number1
StatePublished - 1995
Externally publishedYes

Fingerprint

Ectopic Pregnancy
Spontaneous Abortion
Tissue Banks
Fetus
Transplantation
Obstetrics
Aborted Fetus
National Institutes of Health (U.S.)
Cytogenetics
Therapeutics
Embryonic Structures
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Branch, D. W., Ducat, L., Fantel, A., Low, W. C., Zhou, F., Dayton, D. H., & Gill, T. J. (1995). Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation. Journal of the American Medical Association, 273(1), 66-68.

Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation. / Branch, D. W.; Ducat, L.; Fantel, A.; Low, W. C.; Zhou, Feng; Dayton, D. H.; Gill, T. J.

In: Journal of the American Medical Association, Vol. 273, No. 1, 1995, p. 66-68.

Research output: Contribution to journalArticle

Branch, D. W. ; Ducat, L. ; Fantel, A. ; Low, W. C. ; Zhou, Feng ; Dayton, D. H. ; Gill, T. J. / Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation. In: Journal of the American Medical Association. 1995 ; Vol. 273, No. 1. pp. 66-68.
@article{a52f77c1aa1546218fe2660972558b1c,
title = "Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation",
abstract = "Objective. - To assess the potential availability and utility of fetal tissues obtained from spontaneous abortions and from ectopic pregnancies for human transplantation therapy. Design. - Tissue collection and analysis by personnel skilled in tissue banking. Setting. - Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health. Patients. - All women entering obstetric clinics during 1993 who consented to participate in the study. Interventions. - None. Main Outcome Measures. - Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria. Results. - From 22 235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5{\%}) were potentially useful for human transplantation therapy. Conclusion. - Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.",
author = "Branch, {D. W.} and L. Ducat and A. Fantel and Low, {W. C.} and Feng Zhou and Dayton, {D. H.} and Gill, {T. J.}",
year = "1995",
language = "English (US)",
volume = "273",
pages = "66--68",
journal = "JAMA - Journal of the American Medical Association",
issn = "0002-9955",
publisher = "American Medical Association",
number = "1",

}

TY - JOUR

T1 - Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation

AU - Branch, D. W.

AU - Ducat, L.

AU - Fantel, A.

AU - Low, W. C.

AU - Zhou, Feng

AU - Dayton, D. H.

AU - Gill, T. J.

PY - 1995

Y1 - 1995

N2 - Objective. - To assess the potential availability and utility of fetal tissues obtained from spontaneous abortions and from ectopic pregnancies for human transplantation therapy. Design. - Tissue collection and analysis by personnel skilled in tissue banking. Setting. - Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health. Patients. - All women entering obstetric clinics during 1993 who consented to participate in the study. Interventions. - None. Main Outcome Measures. - Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria. Results. - From 22 235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5%) were potentially useful for human transplantation therapy. Conclusion. - Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.

AB - Objective. - To assess the potential availability and utility of fetal tissues obtained from spontaneous abortions and from ectopic pregnancies for human transplantation therapy. Design. - Tissue collection and analysis by personnel skilled in tissue banking. Setting. - Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health. Patients. - All women entering obstetric clinics during 1993 who consented to participate in the study. Interventions. - None. Main Outcome Measures. - Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria. Results. - From 22 235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5%) were potentially useful for human transplantation therapy. Conclusion. - Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.

UR - http://www.scopus.com/inward/record.url?scp=0028831905&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028831905&partnerID=8YFLogxK

M3 - Article

VL - 273

SP - 66

EP - 68

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

SN - 0002-9955

IS - 1

ER -