Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy

T. S. Herman, Lawrence Einhorn, S. E. Jones, C. Nagy, A. B. Chester, J. C. Dean, B. Furnas, S. D. Williams, S. A. Leigh, R. T. Dorr, T. E. Moon

Research output: Contribution to journalArticle

149 Citations (Scopus)

Abstract

Two double-blind, crossover trials comparing the antiemetic effectiveness of nabilone, a new synthetic cannabinoid, with that of prochlorperazine were conducted in patients with severe nausea and vomiting associated with anticancer chemotherapy. Of 113 patients evaluated, 90 (80%) responded to nabilone therapy, whereas only 36 (32%) responded to prochlorperazine (P

Original languageEnglish (US)
Pages (from-to)1295-1297
Number of pages3
JournalNew England Journal of Medicine
Volume300
Issue number23
StatePublished - 1979
Externally publishedYes

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Prochlorperazine
Antiemetics
Drug Therapy
Cannabinoids
Cross-Over Studies
Nausea
Vomiting
Neoplasms
nabilone
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Herman, T. S., Einhorn, L., Jones, S. E., Nagy, C., Chester, A. B., Dean, J. C., ... Moon, T. E. (1979). Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. New England Journal of Medicine, 300(23), 1295-1297.

Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. / Herman, T. S.; Einhorn, Lawrence; Jones, S. E.; Nagy, C.; Chester, A. B.; Dean, J. C.; Furnas, B.; Williams, S. D.; Leigh, S. A.; Dorr, R. T.; Moon, T. E.

In: New England Journal of Medicine, Vol. 300, No. 23, 1979, p. 1295-1297.

Research output: Contribution to journalArticle

Herman, TS, Einhorn, L, Jones, SE, Nagy, C, Chester, AB, Dean, JC, Furnas, B, Williams, SD, Leigh, SA, Dorr, RT & Moon, TE 1979, 'Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy', New England Journal of Medicine, vol. 300, no. 23, pp. 1295-1297.
Herman, T. S. ; Einhorn, Lawrence ; Jones, S. E. ; Nagy, C. ; Chester, A. B. ; Dean, J. C. ; Furnas, B. ; Williams, S. D. ; Leigh, S. A. ; Dorr, R. T. ; Moon, T. E. / Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. In: New England Journal of Medicine. 1979 ; Vol. 300, No. 23. pp. 1295-1297.
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