Surgical biomaterials and differential colonization by Staphylococcus epidermidis

M. Oga, Y. Sugioka, Cherri Hobgood, A. G. Gristina, Q. N. Myrvik

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

The data presented in this communication demonstrate preferential colonization of certain biomaterials by Staphylococcus epidermidis. Using a laminar flow biomaterial colonization chamber and surgical-grade biomaterials (stainless steel, aluminium ceramic, methyl methacrylate and high-density polyethylene), the pattern of colonization was quantitated using plate count techniques and electron microscopy. Under comparable conditions, methyl methacrylate was colonized by S. epidermidis in greater numbers than the other biomaterials. Increased bacterial colonization and slime production on methyl methacrylate was time-dependent and 15 times higher than on stainless steel and aluminium and four times higher than on high-density polyethylene. The data reveal that certain biomaterials may promote infection by favouring colonization by potential pathogens. This variable should be explored extensively in an in vivo setting because of its implication in clinical infections.

Original languageEnglish (US)
Pages (from-to)285-289
Number of pages5
JournalBiomaterials
Volume9
Issue number3
DOIs
StatePublished - 1988
Externally publishedYes

Fingerprint

Staphylococcus epidermidis
Biocompatible Materials
Biomaterials
Methacrylates
Stainless Steel
Polyethylene
High density polyethylenes
Aluminum
Stainless steel
Ceramics
Pathogens
Infection
Laminar flow
Electron microscopy
Electron Microscopy
Communication

Keywords

  • bacterial adhesion
  • preferential colonization
  • Staphylococcus epidermidis
  • Surgical biomaterials

ASJC Scopus subject areas

  • Bioengineering
  • Ceramics and Composites
  • Biophysics
  • Biomaterials
  • Mechanics of Materials

Cite this

Surgical biomaterials and differential colonization by Staphylococcus epidermidis. / Oga, M.; Sugioka, Y.; Hobgood, Cherri; Gristina, A. G.; Myrvik, Q. N.

In: Biomaterials, Vol. 9, No. 3, 1988, p. 285-289.

Research output: Contribution to journalArticle

Oga, M. ; Sugioka, Y. ; Hobgood, Cherri ; Gristina, A. G. ; Myrvik, Q. N. / Surgical biomaterials and differential colonization by Staphylococcus epidermidis. In: Biomaterials. 1988 ; Vol. 9, No. 3. pp. 285-289.
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