Surgical techniques and outcomes for primary nonseminomatous germ cell tumors

Cameron D. Wright, Kenneth A. Kesler

Research output: Contribution to journalReview article

9 Scopus citations


Patients with primary mediastinal nonseminomatous germ cell tumors are usually young men with large anterior mediastinal masses. The diagnosis can usually be established with measurement of serum tumor markers and a fine-needle aspiration biopsy. The mainstay of treatment is cisplatin-based chemotherapy. Resection of the residual postchemotherapy mass is usually necessary and is performed even with persistently elevated tumor markers if a clean resection is possible. The finding of necrotic tumor predicts long-term survival, whereas persistent germ cell cancer has a less favorable prognosis.

Original languageEnglish (US)
Pages (from-to)707-715
Number of pages9
JournalChest Surgery Clinics of North America
Issue number4
StatePublished - Nov 2002

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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