Susceptibility of partially desalivated rats to erosive tooth wear by calcium-supplemented beverages

M. A. Aldosari, T. Scaramucci, S. S.Y. Liu, J. M. Warrick-Polackoff, G. J. Eckert, A. T. Hara

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Objectives: To investigate the susceptibility of partially desalivated rats to erosive tooth wear (ETW); the anti-erosive effect of a calcium-supplemented beverage; and the quantification of ETW by microcomputed tomography (micro-CT). Methods: The study population consisted of thirty-eight rats, divided into partially desalivated (n = 19) and normal salivary flow (n = 19). They were randomly allocated into three subgroups (n = 6–7): A-diet soda, B-diet soda + calcium, C-water (control). Solutions were provided ad libitum for 28 days, and the rats were euthanized afterwards. Each left hemi-mandible was scanned using micro-CT for enamel volume (three molars) calculation. Visual analysis of photographs of the lingual surface of first molars was performed independently by three blinded examiners. Data were statistically analysed (α =.05). Results: Micro-CT revealed no significant differences between partially desalivated or normal groups. Rats consuming A had more enamel loss than those consuming B or C, which did not differ from each other. For visual analysis, desalivation did not affect ETW. Rats consuming C showed the lowest ETW, followed by B and then A, for both partially desalivated and normal rats. Spearman correlation between the two ETW quantification methods was −.65. Conclusions: Partial desalivation did not increase ETW. Ca-containing beverage prevented ETW. Micro-CT quantified ETW, although it was not as sensitive as visual analysis.

Original languageEnglish (US)
Pages (from-to)355-362
Number of pages8
JournalOral Diseases
Volume24
Issue number3
DOIs
StatePublished - Apr 2018

Keywords

  • animal model
  • calcium
  • dental erosion
  • hyposalivation
  • microcomputed tomography
  • saliva

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Dentistry(all)

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    Aldosari, M. A., Scaramucci, T., Liu, S. S. Y., Warrick-Polackoff, J. M., Eckert, G. J., & Hara, A. T. (2018). Susceptibility of partially desalivated rats to erosive tooth wear by calcium-supplemented beverages. Oral Diseases, 24(3), 355-362. https://doi.org/10.1111/odi.12740