Susceptibility of partially desalivated rats to erosive tooth wear by calcium-supplemented beverages

M. A. Aldosari, T. Scaramucci, S. S.Y. Liu, J. M. Warrick-Polackoff, G. J. Eckert, Anderson Hara

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objectives: To investigate the susceptibility of partially desalivated rats to erosive tooth wear (ETW); the anti-erosive effect of a calcium-supplemented beverage; and the quantification of ETW by microcomputed tomography (micro-CT). Methods: The study population consisted of thirty-eight rats, divided into partially desalivated (n = 19) and normal salivary flow (n = 19). They were randomly allocated into three subgroups (n = 6-7): A-diet soda, B-diet soda + calcium, C-water (control). Solutions were provided ad libitum for 28 days, and the rats were euthanized afterwards. Each left hemi-mandible was scanned using micro-CT for enamel volume (three molars) calculation. Visual analysis of photographs of the lingual surface of first molars was performed independently by three blinded examiners. Data were statistically analysed (α = .05). Results: Micro-CT revealed no significant differences between partially desalivated or normal groups. Rats consuming A had more enamel loss than those consuming B or C, which did not differ from each other. For visual analysis, desalivation did not affect ETW. Rats consuming C showed the lowest ETW, followed by B and then A, for both partially desalivated and normal rats. Spearman correlation between the two ETW quantification methods was -.65. Conclusions: Partial desalivation did not increase ETW. Ca-containing beverage prevented ETW. Micro-CT quantified ETW, although it was not as sensitive as visual analysis.

Original languageEnglish (US)
JournalOral Diseases
DOIs
StateAccepted/In press - Jan 1 2017

Fingerprint

Tooth Wear
Beverages
Calcium
X-Ray Microtomography
Dental Enamel
Diet
Mandible
Tongue

Keywords

  • Animal model
  • Calcium
  • Dental erosion
  • Hyposalivation
  • Microcomputed tomography
  • Saliva

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Dentistry(all)

Cite this

Aldosari, M. A., Scaramucci, T., Liu, S. S. Y., Warrick-Polackoff, J. M., Eckert, G. J., & Hara, A. (Accepted/In press). Susceptibility of partially desalivated rats to erosive tooth wear by calcium-supplemented beverages. Oral Diseases. https://doi.org/10.1111/odi.12740

Susceptibility of partially desalivated rats to erosive tooth wear by calcium-supplemented beverages. / Aldosari, M. A.; Scaramucci, T.; Liu, S. S.Y.; Warrick-Polackoff, J. M.; Eckert, G. J.; Hara, Anderson.

In: Oral Diseases, 01.01.2017.

Research output: Contribution to journalArticle

Aldosari, M. A. ; Scaramucci, T. ; Liu, S. S.Y. ; Warrick-Polackoff, J. M. ; Eckert, G. J. ; Hara, Anderson. / Susceptibility of partially desalivated rats to erosive tooth wear by calcium-supplemented beverages. In: Oral Diseases. 2017.
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