Symptom resolution after hysterectomy and alternative treatments for chronic pelvic pain: Does depression make a difference?

Lee A. Learman, Steven E. Gregorich, Michael Schembri, Alison Jacoby, Rebecca A. Jackson, Miriam Kuppermann

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Objective: The purpose of this study was to determine whether depression influences treatment outcomes and to identify predictors of symptom resolution among women with chronic pelvic pain (CPP). Study Design: Analysis of 701 women with CPP in the Study of Pelvic Problems, Hysterectomy and Intervention Alternatives prospective cohort study, which included 153 women (22%) with depression. We conducted multivariable analyses to evaluate the influence of depression on pre-/posttreatment differences in symptoms and health-related quality of life and to identify other predictors of symptom improvement. Results: CPP treatments included hysterectomy (9%), other surgical treatments (9%), hormonal medications (50%), narcotic analgesics (47%), physical therapy (12%), and nonprescription medications (93%). Depression predicted lower gains in health perception (P < .05) but not in symptom resolution, sexual functioning, or other aspects of health-related quality of life. Symptom resolution was predicted by hysterectomy (P < .001), entering menopause (P < .001), and pretreatment satisfaction with sex (P = .039). Conclusion: Depression does not influence substantially treatment-related gains in CPP symptom resolution and health-related quality of life. Coexisting depression should not delay treatment for CPP.

Original languageEnglish (US)
Pages (from-to)269.e1-269.e9
JournalAmerican Journal of Obstetrics and Gynecology
Volume204
Issue number3
DOIs
StatePublished - Mar 2011

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Symptom resolution after hysterectomy and alternative treatments for chronic pelvic pain: Does depression make a difference?'. Together they form a unique fingerprint.

  • Cite this