Synaptic contact curvature: effects of differential rearing on rat occipital cortex

Janice M. Wesa, Fen Lei F. Chang, William T. Greenough, Roger W. West

Research output: Contribution to journalArticle

41 Scopus citations

Abstract

Synaptic contact curvature has been proposed as an index of synaptic efficacy or maturity. In this report, members of 11 triplet sets of hooded rats were reared for 30 days postweaning in environmental complexity (EC), social cages (SC), or isolation cages (IC). Synapses from EC visual cortex showed the greatest presynaptic concavity while the IC visual cortical synapses showed the least. This result both suggests that curvature may reflect a functional aspect of the synapse and raises the possibility that other measures, such as synaptic size and density could be confounded by differential curvature.

Original languageEnglish (US)
Pages (from-to)253-257
Number of pages5
JournalDevelopmental Brain Research
Volume4
Issue number2
DOIs
StatePublished - Jun 1982
Externally publishedYes

Keywords

  • electron microscopy
  • enriched environment
  • rat
  • synaptic curvature
  • synaptic efficacy
  • visual cortex

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Developmental Biology

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