Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase

L. Cappellacci, P. Franchetti, G. Abu Sheikha, H. N. Jayaram, V. V. Gurudutt, T. Sint, B. P. Schneider, B. M. Goldstein, G. Perra, S. Poma, P. La Colla, M. Grifantini

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The synthesis of 5-β-D-ribofuranosylselenophene-3-carboxamide (selenophenfurin) is reported. Selenophenfurin was found active as cytotoxic agent and as inosine monophosphate dehydrogenase inhibitor.

Original languageEnglish (US)
Pages (from-to)1045-1048
Number of pages4
JournalNucleosides and Nucleotides
Volume16
Issue number7-9
DOIs
StatePublished - Jan 1 1997

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IMP Dehydrogenase
Inosine Monophosphate
Cytotoxins
Oxidoreductases
selenophenfurin

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

Cite this

Cappellacci, L., Franchetti, P., Abu Sheikha, G., Jayaram, H. N., Gurudutt, V. V., Sint, T., ... Grifantini, M. (1997). Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase. Nucleosides and Nucleotides, 16(7-9), 1045-1048. https://doi.org/10.1080/07328319708006129

Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase. / Cappellacci, L.; Franchetti, P.; Abu Sheikha, G.; Jayaram, H. N.; Gurudutt, V. V.; Sint, T.; Schneider, B. P.; Goldstein, B. M.; Perra, G.; Poma, S.; La Colla, P.; Grifantini, M.

In: Nucleosides and Nucleotides, Vol. 16, No. 7-9, 01.01.1997, p. 1045-1048.

Research output: Contribution to journalArticle

Cappellacci, L, Franchetti, P, Abu Sheikha, G, Jayaram, HN, Gurudutt, VV, Sint, T, Schneider, BP, Goldstein, BM, Perra, G, Poma, S, La Colla, P & Grifantini, M 1997, 'Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase', Nucleosides and Nucleotides, vol. 16, no. 7-9, pp. 1045-1048. https://doi.org/10.1080/07328319708006129
Cappellacci L, Franchetti P, Abu Sheikha G, Jayaram HN, Gurudutt VV, Sint T et al. Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase. Nucleosides and Nucleotides. 1997 Jan 1;16(7-9):1045-1048. https://doi.org/10.1080/07328319708006129
Cappellacci, L. ; Franchetti, P. ; Abu Sheikha, G. ; Jayaram, H. N. ; Gurudutt, V. V. ; Sint, T. ; Schneider, B. P. ; Goldstein, B. M. ; Perra, G. ; Poma, S. ; La Colla, P. ; Grifantini, M. / Synthesis and cytotoxic activity of selenophenfurin, a new inhibitor of IMP dehydrogenase. In: Nucleosides and Nucleotides. 1997 ; Vol. 16, No. 7-9. pp. 1045-1048.
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