Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin

P. Franchetti, L. Cappellacci, G. Abu Sheikha, H. N. Jayaram, B. P. Schneider, T. Sint, V. V. Gurudutt, F. R. Collart, E. Huberman, M. Grifantini

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Thiophene-3-carboxamide adenine dinucleotide (TFAD), and furan-3- carboxamide adenine dinucleotide (FFAD), two NAD analogs, were synthesized and evaluated as inhibitors of inosine monophosphate dehydrogenase type I and type II.

Original languageEnglish (US)
Pages (from-to)1415-1418
Number of pages4
JournalNucleosides and Nucleotides
Volume16
Issue number7-9
DOIs
StatePublished - Jan 1 1997

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

Fingerprint Dive into the research topics of 'Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin'. Together they form a unique fingerprint.

  • Cite this

    Franchetti, P., Cappellacci, L., Abu Sheikha, G., Jayaram, H. N., Schneider, B. P., Sint, T., Gurudutt, V. V., Collart, F. R., Huberman, E., & Grifantini, M. (1997). Synthesis and IMP dehydrogenase (type I and type II) inhibitory activity of isosteric NAD analogs derived from thiophenfurin and furanfurin. Nucleosides and Nucleotides, 16(7-9), 1415-1418. https://doi.org/10.1080/07328319708006195