Systemic beta-interferon therapy for recurrent gliomas: A brief report

M. S. Mahaley, E. J. Dropcho, L. Bertsch, T. Tirey, G. Y. Gillespie

Research output: Contribution to journalArticle

16 Scopus citations


Recombinant beta-interferon in escalating dosages was administered intravenously three times weekly to seven patients with recurrent gliomas. No evidence of response was seen in any patient, either on neurological examination or by computerized tomography (CT). However, stabilization of tumor volume, assessed from contrast-enhanced CT scans, occurred for 8 to 26 weeks in three patients. Immediate progression of disease despite treatment occurred in four patients.

Original languageEnglish (US)
Pages (from-to)639-641
Number of pages3
JournalJournal of neurosurgery
Issue number5 I
StatePublished - Jan 1 1989
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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