Temporal processing dysfunction in schizophrenia

Christine A. Carroll, Jennifer Boggs, Brian O'Donnell, Anantha Shekhar, William P. Hetrick

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

Schizophrenia may be associated with a fundamental disturbance in the temporal coordination of information processing in the brain, leading to classic symptoms of schizophrenia such as thought disorder and disorganized and contextually inappropriate behavior. Despite the growing interest and centrality of time-dependent conceptualizations of the pathophysiology of schizophrenia, there remains a paucity of research directly examining overt timing performance in the disorder. Accordingly, the present study investigated timing in schizophrenia using a well-established task of time perception. Twenty-three individuals with schizophrenia and 22 non-psychiatric control participants completed a temporal bisection task, which required participants to make temporal judgments about auditory and visually presented durations ranging from 300 to 600 ms. Both schizophrenia and control groups displayed greater visual compared to auditory timing variability, with no difference between groups in the visual modality. However, individuals with schizophrenia exhibited less temporal precision than controls in the perception of auditory durations. These findings correlated with parameter estimates obtained from a quantitative model of time estimation, and provide evidence of a fundamental deficit in temporal auditory precision in schizophrenia.

Original languageEnglish
Pages (from-to)150-161
Number of pages12
JournalBrain and Cognition
Volume67
Issue number2
DOIs
StatePublished - Jul 2008

Fingerprint

Schizophrenia
Auditory Perception
Time Perception
Temporal Processing
Automatic Data Processing
Control Groups
Hearing
Brain
Research

Keywords

  • Schizophrenia
  • Temporal coordination
  • Temporal processing
  • Timing
  • Variability

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

Cite this

Temporal processing dysfunction in schizophrenia. / Carroll, Christine A.; Boggs, Jennifer; O'Donnell, Brian; Shekhar, Anantha; Hetrick, William P.

In: Brain and Cognition, Vol. 67, No. 2, 07.2008, p. 150-161.

Research output: Contribution to journalArticle

Carroll, Christine A. ; Boggs, Jennifer ; O'Donnell, Brian ; Shekhar, Anantha ; Hetrick, William P. / Temporal processing dysfunction in schizophrenia. In: Brain and Cognition. 2008 ; Vol. 67, No. 2. pp. 150-161.
@article{75ed531e527c48d7bb1f6d3dacdefe77,
title = "Temporal processing dysfunction in schizophrenia",
abstract = "Schizophrenia may be associated with a fundamental disturbance in the temporal coordination of information processing in the brain, leading to classic symptoms of schizophrenia such as thought disorder and disorganized and contextually inappropriate behavior. Despite the growing interest and centrality of time-dependent conceptualizations of the pathophysiology of schizophrenia, there remains a paucity of research directly examining overt timing performance in the disorder. Accordingly, the present study investigated timing in schizophrenia using a well-established task of time perception. Twenty-three individuals with schizophrenia and 22 non-psychiatric control participants completed a temporal bisection task, which required participants to make temporal judgments about auditory and visually presented durations ranging from 300 to 600 ms. Both schizophrenia and control groups displayed greater visual compared to auditory timing variability, with no difference between groups in the visual modality. However, individuals with schizophrenia exhibited less temporal precision than controls in the perception of auditory durations. These findings correlated with parameter estimates obtained from a quantitative model of time estimation, and provide evidence of a fundamental deficit in temporal auditory precision in schizophrenia.",
keywords = "Schizophrenia, Temporal coordination, Temporal processing, Timing, Variability",
author = "Carroll, {Christine A.} and Jennifer Boggs and Brian O'Donnell and Anantha Shekhar and Hetrick, {William P.}",
year = "2008",
month = "7",
doi = "10.1016/j.bandc.2007.12.005",
language = "English",
volume = "67",
pages = "150--161",
journal = "Brain and Cognition",
issn = "0278-2626",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Temporal processing dysfunction in schizophrenia

AU - Carroll, Christine A.

AU - Boggs, Jennifer

AU - O'Donnell, Brian

AU - Shekhar, Anantha

AU - Hetrick, William P.

PY - 2008/7

Y1 - 2008/7

N2 - Schizophrenia may be associated with a fundamental disturbance in the temporal coordination of information processing in the brain, leading to classic symptoms of schizophrenia such as thought disorder and disorganized and contextually inappropriate behavior. Despite the growing interest and centrality of time-dependent conceptualizations of the pathophysiology of schizophrenia, there remains a paucity of research directly examining overt timing performance in the disorder. Accordingly, the present study investigated timing in schizophrenia using a well-established task of time perception. Twenty-three individuals with schizophrenia and 22 non-psychiatric control participants completed a temporal bisection task, which required participants to make temporal judgments about auditory and visually presented durations ranging from 300 to 600 ms. Both schizophrenia and control groups displayed greater visual compared to auditory timing variability, with no difference between groups in the visual modality. However, individuals with schizophrenia exhibited less temporal precision than controls in the perception of auditory durations. These findings correlated with parameter estimates obtained from a quantitative model of time estimation, and provide evidence of a fundamental deficit in temporal auditory precision in schizophrenia.

AB - Schizophrenia may be associated with a fundamental disturbance in the temporal coordination of information processing in the brain, leading to classic symptoms of schizophrenia such as thought disorder and disorganized and contextually inappropriate behavior. Despite the growing interest and centrality of time-dependent conceptualizations of the pathophysiology of schizophrenia, there remains a paucity of research directly examining overt timing performance in the disorder. Accordingly, the present study investigated timing in schizophrenia using a well-established task of time perception. Twenty-three individuals with schizophrenia and 22 non-psychiatric control participants completed a temporal bisection task, which required participants to make temporal judgments about auditory and visually presented durations ranging from 300 to 600 ms. Both schizophrenia and control groups displayed greater visual compared to auditory timing variability, with no difference between groups in the visual modality. However, individuals with schizophrenia exhibited less temporal precision than controls in the perception of auditory durations. These findings correlated with parameter estimates obtained from a quantitative model of time estimation, and provide evidence of a fundamental deficit in temporal auditory precision in schizophrenia.

KW - Schizophrenia

KW - Temporal coordination

KW - Temporal processing

KW - Timing

KW - Variability

UR - http://www.scopus.com/inward/record.url?scp=44649135316&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=44649135316&partnerID=8YFLogxK

U2 - 10.1016/j.bandc.2007.12.005

DO - 10.1016/j.bandc.2007.12.005

M3 - Article

C2 - 18262701

AN - SCOPUS:44649135316

VL - 67

SP - 150

EP - 161

JO - Brain and Cognition

JF - Brain and Cognition

SN - 0278-2626

IS - 2

ER -