Testicular plasmacytoma misdiagnosed as orchitis

Christopher Schiavo, Steven Alexander Mann, Jesse Mer, Attaya Suvannasankha

Research output: Contribution to journalArticle

Abstract

Testicular plasmacytomas are rare, accounting for only 1.3% of all extramedullary plasmacytomas. The infrequency in which it is encountered, coupled with its non-specific clinical and sonographic presentation, makes its diagnosis a challenge. We present a case of a 70-year-old man with multiple myeloma, which was systemically responding to chemotherapy, who developed testicular swelling, erythema and pain. Ultrasound findings were concerning for infection, although urine and serum testing were unremarkable. The patient did not improve after several rounds of antibiotics prompting further evaluation. The patient underwent radical orchiectomy which revealed testicular plasmacytoma. Fluorescent in situ hybridisation (FISH) of the testicular tissue noted mutations which had not been present in the FISH analysis of bone marrow. Positron emission tomography scan later revealed new retroperitoneal plasmacytomas involving the new clone and his chemotherapy regimen needed to be adjusted for treatment.

Original languageEnglish (US)
Article number222046
JournalBMJ Case Reports
Volume2018
DOIs
StatePublished - Jan 1 2018

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Orchitis
Plasmacytoma
Diagnostic Errors
Fluorescence In Situ Hybridization
Drug Therapy
Orchiectomy
Erythema
Multiple Myeloma
Positron-Emission Tomography
Clone Cells
Bone Marrow
Urine
Anti-Bacterial Agents
Pain
Mutation
Infection
Serum

Keywords

  • cancer intervention
  • haematology (incl blood transfusion)
  • radiology

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Testicular plasmacytoma misdiagnosed as orchitis. / Schiavo, Christopher; Mann, Steven Alexander; Mer, Jesse; Suvannasankha, Attaya.

In: BMJ Case Reports, Vol. 2018, 222046, 01.01.2018.

Research output: Contribution to journalArticle

Schiavo, Christopher ; Mann, Steven Alexander ; Mer, Jesse ; Suvannasankha, Attaya. / Testicular plasmacytoma misdiagnosed as orchitis. In: BMJ Case Reports. 2018 ; Vol. 2018.
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