Testicular ultrasonography after chemotherapy for germ cell neoplasm: Significance of highly hyperechoic lesions

Kenyon K. Kopecky, Michael T. Brendle, Jon T. Harman, Richard S. Foster, Richard Bihrle, Patrick J. Loehrer

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The sonographic appearance of the testis after administration of chemotherapy for metastatic germ cell neoplasm is not well known. Fifty-six patients (60 testes) who were previously treated with chemotherapy for metastatic germ cell neoplasm (originally diagnosed by removal of the contralateral testis or by biopsy of metastatic disease) underwent sonography followed by orchiectomy. The sonographic characteristics found to predict viable intratesticular tumor were: lesion size larger than 5 mm, fewer echoes than adjacent parenchyma (hypoechoic), inhomogeneous echo texture, poor margin definition, cystic areas, or highly hyperechoic foci within a hypoechoic lesion. Fibrosis was predicted by finding single or multiple small, highly hyperechoic lesions. These results suggest the potential for predicting the pathologic diagnosis in some patients after receiving chemotherapy for germ cell neoplasm.

Original languageEnglish (US)
Pages (from-to)490-494
Number of pages5
JournalUrology
Volume39
Issue number5
DOIs
StatePublished - May 1992

ASJC Scopus subject areas

  • Urology

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