The 20,000-dalton variant of human growth hormone: Location of the amino acid deletions

U. J. Lewis, Lynda Bonewald, L. J. Lewis

Research output: Contribution to journalArticle

136 Citations (Scopus)

Abstract

The 20,000-dalton variant of human growth hormone lacks a sequence of 15 amino acids normally found in the hormone. The deletion involves residues 32 through 46. The remainder of the molecule is identical to the larger form of the hormone. These results suggest that the variant is the product of a deletion mutation in the growth hormone gene.

Original languageEnglish (US)
Pages (from-to)511-516
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume92
Issue number2
DOIs
StatePublished - Jan 29 1980
Externally publishedYes

Fingerprint

Human Growth Hormone
Hormones
Amino Acids
Sequence Deletion
Growth Hormone
Amino Acid Sequence
Genes
Molecules

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

The 20,000-dalton variant of human growth hormone : Location of the amino acid deletions. / Lewis, U. J.; Bonewald, Lynda; Lewis, L. J.

In: Biochemical and Biophysical Research Communications, Vol. 92, No. 2, 29.01.1980, p. 511-516.

Research output: Contribution to journalArticle

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