The acceptability of HIV immunization: Examining vaccine characteristics as determining factors

A. Liau, Gregory Zimet

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The acceptance of a future HIV vaccine may be influenced, in part, by the characteristics of the vaccine itself. This study evaluated the relationship of vaccine characteristics to acceptability of hypothetical HIV immunization. Subjects were 549 undergraduates (18-56 years of age); 70.3% were female, and 80.4% were non-Hispanic white. Subjects completed a self-administered questionnaire assessing a series of 12 hypothetical vaccines that varied along the dimensions of efficacy (80 or 50%), cost (free or $300) and social saturation or percentage of the population already vaccinated (10, 50 or 90%). The vaccines were each rated on an 11-point scale ranging from zero ('I will never get this vaccine') to 100 ('I will definitely get this vaccine'), in increments of ten. All three dimensions were significantly associated with probability of vaccine acceptance, particularly vaccine efficacy and cost. The highest rated vaccine (free, 80% efficacious, 90% saturation level) received a mean acceptability score of 83.4, whereas the lowest rated vaccine ($300, 50% efficacious, 10% saturation level) received a mean score of 32.8. The mean acceptability rating across all 12 vaccines was 55.14. These findings indicate the potential importance of considering the influence of vaccine characteristics in future HIV immunization programmes.

Original languageEnglish
Pages (from-to)643-650
Number of pages8
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Volume13
Issue number5
DOIs
StatePublished - 2001

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Immunization
Vaccines
acceptance
HIV
costs
rating
questionnaire
Costs and Cost Analysis
AIDS Vaccines
Immunization Programs

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health(social science)
  • Health Professions(all)
  • Social Sciences (miscellaneous)

Cite this

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