The application of immunohistochemical biomarkers in urologic surgical pathology

Myra L. Wilkerson, Fan Lin, Haiyan Liu, Liang Cheng

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Context.-Tumors of the genitourinary tract can be diagnostically challenging, particularly in core biopsies and cystoscopic biopsies with limited material. Immunohistochemistry is a valuable tool to use when morphology alone is insufficient for diagnosis. Objectives.-To review tumors and benign lesions of the kidney, urinary bladder, prostate gland, testis, and paratesticular structures with an emphasis on difficult differential diagnoses, as well as staining patterns in normal tissue. Recommended immunohistochemical stain panels are discussed that can assist in the diagnostic workup. Data Sources.-Review of current literature. Conclusions.-Immunohistochemistry is a valuable tool, assisting in the diagnosis of problematic tumors and benign lesions of the genitourinary tract.

Original languageEnglish
Pages (from-to)1643-1665
Number of pages23
JournalArchives of Pathology and Laboratory Medicine
Volume138
Issue number12
DOIs
StatePublished - Dec 1 2014

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Surgical Pathology
Biomarkers
Immunohistochemistry
Biopsy
Neoplasms
Information Storage and Retrieval
Testis
Prostate
Urinary Bladder
Differential Diagnosis
Coloring Agents
Staining and Labeling
Kidney

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology
  • Medicine(all)

Cite this

The application of immunohistochemical biomarkers in urologic surgical pathology. / Wilkerson, Myra L.; Lin, Fan; Liu, Haiyan; Cheng, Liang.

In: Archives of Pathology and Laboratory Medicine, Vol. 138, No. 12, 01.12.2014, p. 1643-1665.

Research output: Contribution to journalArticle

Wilkerson, Myra L. ; Lin, Fan ; Liu, Haiyan ; Cheng, Liang. / The application of immunohistochemical biomarkers in urologic surgical pathology. In: Archives of Pathology and Laboratory Medicine. 2014 ; Vol. 138, No. 12. pp. 1643-1665.
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