The application of immunohistochemical biomarkers in urologic surgical pathology

Myra L. Wilkerson, Fan Lin, Haiyan Liu, Liang Cheng

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Context.-Tumors of the genitourinary tract can be diagnostically challenging, particularly in core biopsies and cystoscopic biopsies with limited material. Immunohistochemistry is a valuable tool to use when morphology alone is insufficient for diagnosis. Objectives.-To review tumors and benign lesions of the kidney, urinary bladder, prostate gland, testis, and paratesticular structures with an emphasis on difficult differential diagnoses, as well as staining patterns in normal tissue. Recommended immunohistochemical stain panels are discussed that can assist in the diagnostic workup. Data Sources.-Review of current literature. Conclusions.-Immunohistochemistry is a valuable tool, assisting in the diagnosis of problematic tumors and benign lesions of the genitourinary tract.

Original languageEnglish (US)
Pages (from-to)1643-1665
Number of pages23
JournalArchives of Pathology and Laboratory Medicine
Volume138
Issue number12
DOIs
StatePublished - Dec 1 2014

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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