The architecture of cancellous and cortical bone in femoral neck fracture

L. D. Hordon, M. Peacock

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

The architecture of cancellous bone as well as quantity and quality is considered important in maintaining mechanical integrity. To determine whether abnormalities of architecture occur in femoral neck fracture we measured trabecular width and number in iliac crest bone biopsies of 68 women with femoral fracture and compared them with data from a postmortem series of age-matched women without known bone disease. Cortical thickness was measured in 27 of the fracture patients and 17 controls. After exclusion of ten biopsies with increased osteoid surface no significant difference was seen in mean trabecular width or number between fracture patients and subjects without fracture. Both thinning of trabeculae and loss of trabeculae contributed to low bone volume in femoral fracture patients. Direct measurements of trabecular number correlated with calculated mean trabocular plate density (P < 0.001), and the percentage of trabeculae at any one of a range of trabecular widths in the fracture biopsies was similar to that in non-fracture subjects. No difference was seen in the architecture of cancellous bone with age, fracture trauma or between subcapital and intertochanteric fracture in fracture subjects. Cortical thickness, however, was related to age in both fracture and control subjects (P < 0.05). There was no difference in cortical thickness between age-matched fracture and control subjects. Patients with intertrochanteric fracture had lower cortical thickness (P < 0.02) and were older (P < 0.01) than patients with subcapital fracture.

Original languageEnglish (US)
Pages (from-to)335-345
Number of pages11
JournalBone and Mineral
Volume11
Issue number3
DOIs
StatePublished - Dec 1990

Keywords

  • Cortical thickness
  • Femoral fracture
  • Iliac crest biopsy
  • Osteoporosis
  • Trabecular number
  • Trabecular width

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Surgery

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