The ATC (ataxia-telangiectasia complementation group C) locus localizes to 11q22-q23

Yael Ziv, Galit Rotman, Moshe Frydman, Judith Dagan, Tirza Cohen, Tatiana Foroud, Richard A. Gatti, Yosef Shiloh

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

The multisystem autosomal recessive disease ataxia-telangiectasia (A-T) is determined by several genes, as evidenced by the existence of four complementation groups in this disorder. Using linkage analysis, the ATA (A-T complementation group A) gene was previously localized to chromosome 11, region q22-q23. Analysis of the segregation of RFLP markers from this region in a Jewish-Moroccan family assigned to group C indicates that the ATC (A-T complementation group C) gene localizes to chromosome 11q22-q23 as well.

Original languageEnglish (US)
Pages (from-to)373-375
Number of pages3
JournalGenomics
Volume9
Issue number2
DOIs
StatePublished - Feb 1991
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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    Ziv, Y., Rotman, G., Frydman, M., Dagan, J., Cohen, T., Foroud, T., Gatti, R. A., & Shiloh, Y. (1991). The ATC (ataxia-telangiectasia complementation group C) locus localizes to 11q22-q23. Genomics, 9(2), 373-375. https://doi.org/10.1016/0888-7543(91)90268-J