The complete nucleotide sequence of the ilvGMEDA operon of Escherichia Coli K-12

Robert P. Lawther, Ronald C. Wek, John M. Lopes, Ruth Perira, Bruce E. Taillon, G. Wesley

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Abstract

In this report we present the complete nucleotlde sequence of the ilvGMEDA operon of Escherichia coll. This operon contains five genes encoding four of the five enzymes required for the biosynthesis of isoleucine and valine. We identify and describe the coding regions for these five structural genes and the structural and functional features of the flanking and internal regulatory regions of this operon. This new information contributes to a more complete understanding of the overall control of the biosynthesis of isoleucine and valine.

Original languageEnglish (US)
Pages (from-to)2137-2155
Number of pages19
JournalNucleic acids research
Volume15
Issue number5
DOIs
StatePublished - Mar 15 1987

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ASJC Scopus subject areas

  • Genetics

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Lawther, R. P., Wek, R. C., Lopes, J. M., Perira, R., Taillon, B. E., & Wesley, G. (1987). The complete nucleotide sequence of the ilvGMEDA operon of Escherichia Coli K-12. Nucleic acids research, 15(5), 2137-2155. https://doi.org/10.1093/nar/15.5.2137