The complete nucleotide sequence of the ilvGMEDA operon of Escherichia Coli K-12

Robert P. Lawther, Ronald Wek, John M. Lopes, Ruth Perira, Bruce E. Taillon, G. Wesley

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

In this report we present the complete nucleotlde sequence of the ilvGMEDA operon of Escherichia coll. This operon contains five genes encoding four of the five enzymes required for the biosynthesis of isoleucine and valine. We identify and describe the coding regions for these five structural genes and the structural and functional features of the flanking and internal regulatory regions of this operon. This new information contributes to a more complete understanding of the overall control of the biosynthesis of isoleucine and valine.

Original languageEnglish (US)
Pages (from-to)2137-2155
Number of pages19
JournalNucleic Acids Research
Volume15
Issue number5
DOIs
StatePublished - Mar 15 1987
Externally publishedYes

Fingerprint

Isoleucine
Biosynthesis
Valine
Operon
Nucleotides
Escherichia coli
Escherichia Coli
Gene
Gene encoding
Nucleic Acid Regulatory Sequences
Escherichia
Enzymes
Encoding
Coding
Genes
Internal
Nucleotide sequence

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Health, Toxicology and Mutagenesis
  • Toxicology
  • Genetics(clinical)
  • Genetics

Cite this

Lawther, R. P., Wek, R., Lopes, J. M., Perira, R., Taillon, B. E., & Wesley, G. (1987). The complete nucleotide sequence of the ilvGMEDA operon of Escherichia Coli K-12. Nucleic Acids Research, 15(5), 2137-2155. https://doi.org/10.1093/nar/15.5.2137

The complete nucleotide sequence of the ilvGMEDA operon of Escherichia Coli K-12. / Lawther, Robert P.; Wek, Ronald; Lopes, John M.; Perira, Ruth; Taillon, Bruce E.; Wesley, G.

In: Nucleic Acids Research, Vol. 15, No. 5, 15.03.1987, p. 2137-2155.

Research output: Contribution to journalArticle

Lawther, RP, Wek, R, Lopes, JM, Perira, R, Taillon, BE & Wesley, G 1987, 'The complete nucleotide sequence of the ilvGMEDA operon of Escherichia Coli K-12', Nucleic Acids Research, vol. 15, no. 5, pp. 2137-2155. https://doi.org/10.1093/nar/15.5.2137
Lawther, Robert P. ; Wek, Ronald ; Lopes, John M. ; Perira, Ruth ; Taillon, Bruce E. ; Wesley, G. / The complete nucleotide sequence of the ilvGMEDA operon of Escherichia Coli K-12. In: Nucleic Acids Research. 1987 ; Vol. 15, No. 5. pp. 2137-2155.
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