The complex relationship between pain intensity and physical functioning in fibromyalgia: the mediating role of depression

Jennifer L. Steiner, Silvia Bigatti, James E. Slaven, Dennis C. Ang

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Fibromyalgia (FM) is typically associated with the experience of diffuse pain and physical impairment. Depression also commonly co-exists in patients with FM and has been correlated with pain intensity and physical functioning. Previous research suggests an association between pain intensity and physical functioning; however, the direct causal relationship between improvements in pain intensity and in functioning is not observed in many FM patients. This may suggest that another factor such as depression is mediating this relationship. The present work examined mediating role of depression. Two hundred sixteen patients with FM completed measures of pain intensity, depression, and physical function as part of a larger longitudinal study. Assessments were completed at baseline, 12, 24, and 36 weeks. Longitudinal mediational analyses indicated that depression is a partial mediator of the relationship between pain intensity and physical functioning at all four assessment points. Beta coefficients for the path from pain to physical functioning ranged from 0.18 to 0.36, with attenuated path coefficients ranging 0.03–0.08, still showing significant but decreased associations when depression was added as a mediator. Clinical implication includes the importance of treating comorbid depression in patients with FM early in the course of treatment to prevent engagement in the cycle of disability.

Original languageEnglish (US)
Article numbere12079
JournalJournal of Applied Biobehavioral Research
Volume22
Issue number4
DOIs
StatePublished - Dec 1 2017

Fingerprint

Fibromyalgia
pain
Depression
Pain
Longitudinal Studies
longitudinal study
disability
Research

ASJC Scopus subject areas

  • Cultural Studies
  • Experimental and Cognitive Psychology
  • Clinical Psychology
  • Social Sciences (miscellaneous)

Cite this

The complex relationship between pain intensity and physical functioning in fibromyalgia : the mediating role of depression. / Steiner, Jennifer L.; Bigatti, Silvia; Slaven, James E.; Ang, Dennis C.

In: Journal of Applied Biobehavioral Research, Vol. 22, No. 4, e12079, 01.12.2017.

Research output: Contribution to journalArticle

@article{a04e407ad3b54505b0f5e884c3fc6d5e,
title = "The complex relationship between pain intensity and physical functioning in fibromyalgia: the mediating role of depression",
abstract = "Fibromyalgia (FM) is typically associated with the experience of diffuse pain and physical impairment. Depression also commonly co-exists in patients with FM and has been correlated with pain intensity and physical functioning. Previous research suggests an association between pain intensity and physical functioning; however, the direct causal relationship between improvements in pain intensity and in functioning is not observed in many FM patients. This may suggest that another factor such as depression is mediating this relationship. The present work examined mediating role of depression. Two hundred sixteen patients with FM completed measures of pain intensity, depression, and physical function as part of a larger longitudinal study. Assessments were completed at baseline, 12, 24, and 36 weeks. Longitudinal mediational analyses indicated that depression is a partial mediator of the relationship between pain intensity and physical functioning at all four assessment points. Beta coefficients for the path from pain to physical functioning ranged from 0.18 to 0.36, with attenuated path coefficients ranging 0.03–0.08, still showing significant but decreased associations when depression was added as a mediator. Clinical implication includes the importance of treating comorbid depression in patients with FM early in the course of treatment to prevent engagement in the cycle of disability.",
author = "Steiner, {Jennifer L.} and Silvia Bigatti and Slaven, {James E.} and Ang, {Dennis C.}",
year = "2017",
month = "12",
day = "1",
doi = "10.1111/jabr.12079",
language = "English (US)",
volume = "22",
journal = "Journal of Applied Biobehavioral Research",
issn = "1071-2089",
publisher = "Bellwether Publishing, Ltd.",
number = "4",

}

TY - JOUR

T1 - The complex relationship between pain intensity and physical functioning in fibromyalgia

T2 - the mediating role of depression

AU - Steiner, Jennifer L.

AU - Bigatti, Silvia

AU - Slaven, James E.

AU - Ang, Dennis C.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Fibromyalgia (FM) is typically associated with the experience of diffuse pain and physical impairment. Depression also commonly co-exists in patients with FM and has been correlated with pain intensity and physical functioning. Previous research suggests an association between pain intensity and physical functioning; however, the direct causal relationship between improvements in pain intensity and in functioning is not observed in many FM patients. This may suggest that another factor such as depression is mediating this relationship. The present work examined mediating role of depression. Two hundred sixteen patients with FM completed measures of pain intensity, depression, and physical function as part of a larger longitudinal study. Assessments were completed at baseline, 12, 24, and 36 weeks. Longitudinal mediational analyses indicated that depression is a partial mediator of the relationship between pain intensity and physical functioning at all four assessment points. Beta coefficients for the path from pain to physical functioning ranged from 0.18 to 0.36, with attenuated path coefficients ranging 0.03–0.08, still showing significant but decreased associations when depression was added as a mediator. Clinical implication includes the importance of treating comorbid depression in patients with FM early in the course of treatment to prevent engagement in the cycle of disability.

AB - Fibromyalgia (FM) is typically associated with the experience of diffuse pain and physical impairment. Depression also commonly co-exists in patients with FM and has been correlated with pain intensity and physical functioning. Previous research suggests an association between pain intensity and physical functioning; however, the direct causal relationship between improvements in pain intensity and in functioning is not observed in many FM patients. This may suggest that another factor such as depression is mediating this relationship. The present work examined mediating role of depression. Two hundred sixteen patients with FM completed measures of pain intensity, depression, and physical function as part of a larger longitudinal study. Assessments were completed at baseline, 12, 24, and 36 weeks. Longitudinal mediational analyses indicated that depression is a partial mediator of the relationship between pain intensity and physical functioning at all four assessment points. Beta coefficients for the path from pain to physical functioning ranged from 0.18 to 0.36, with attenuated path coefficients ranging 0.03–0.08, still showing significant but decreased associations when depression was added as a mediator. Clinical implication includes the importance of treating comorbid depression in patients with FM early in the course of treatment to prevent engagement in the cycle of disability.

UR - http://www.scopus.com/inward/record.url?scp=85018588576&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85018588576&partnerID=8YFLogxK

U2 - 10.1111/jabr.12079

DO - 10.1111/jabr.12079

M3 - Article

AN - SCOPUS:85018588576

VL - 22

JO - Journal of Applied Biobehavioral Research

JF - Journal of Applied Biobehavioral Research

SN - 1071-2089

IS - 4

M1 - e12079

ER -