The current and future management of acute heart failure syndromes

Peter Pang, Michel Komajda, Mihai Gheorghiade

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Hospitalization for heart failure (HF) marks a substantial crossroad for patients, as greater than one-third will be re-hospitalized or dead within 90 days post-discharge. For patients with chronic HF who present with acute heart failure syndromes (AHFS), they transition from an arena of well-established and life-saving evidence-based therapies to one where early pharmacological management has changed little over the last 40 years. Traditional therapies, such as oxygen, loop diuretics, nitrates, and morphine remain the cornerstone of early management today. Despite earlier initiation of chronic HF therapies during hospitalization, post-discharge event rates remain high. Optimizing management of known targets with proven evidence-based therapy has the potential to reduce post-discharge event rates. In this inaugural issue of the Frontiers in Cardiovascular Therapy, we briefly review current in-hospital management of AHFS, introduce the concept of cardiac reconstruction, and focus on the potential of future management strategies and therapeutics to improve outcomes in AHFS.

Original languageEnglish (US)
Pages (from-to)784-793
Number of pages10
JournalEuropean Heart Journal
Volume31
Issue number7
DOIs
StatePublished - 2010
Externally publishedYes

Fingerprint

Heart Failure
Hospitalization
Therapeutics
Sodium Potassium Chloride Symporter Inhibitors
Nitrates
Morphine
Pharmacology
Oxygen

Keywords

  • Acute heart failure syndromes
  • Management

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

Cite this

The current and future management of acute heart failure syndromes. / Pang, Peter; Komajda, Michel; Gheorghiade, Mihai.

In: European Heart Journal, Vol. 31, No. 7, 2010, p. 784-793.

Research output: Contribution to journalArticle

Pang, Peter ; Komajda, Michel ; Gheorghiade, Mihai. / The current and future management of acute heart failure syndromes. In: European Heart Journal. 2010 ; Vol. 31, No. 7. pp. 784-793.
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