The development of a semi-structured home interview (CHIF) to directly assess function in cognitively impaired elderly people in two cultures

Hugh Hendrie, K. A. Lane, A. Ogunniyi, O. Baiyewu, O. Gureje, R. Evans, V. Smith-Gamble, M. Pettaway, Frederick Unverzagt, Sujuan Gao, Kathleen Hall

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Background: Assessing function is a crucial element in the diagnosis of dementia. This information is usually obtained from key informants. However, reliable informants are not always available. Methods: A 10-item semi-structured home interview (the CHIF, or Clinician Home-based Interview to assess Function) to assess function primarily by measuring instrumental activities of daily living directly was developed and tested for inter-rater reliability and validity as part of the Indianapolis-Ibadan dementia project. The primary validity measurements were correlations between scores on the CHIF and independently gathered scores on the Blessed Dementia Scale (from informants) and the Mini-mental State Examination (MMSE). Sensitivities and specificities of scores on the CHIF and receiver operator characteristic (ROC) curves were constructed with dementia as the dependent variable. Results: Inter-rater reliability for the CHIF was high (Pearson's correlation coefficient 0.99 in Indianapolis and 0.87 in Ibadan). Internal consistency, in both samples, was good (Cronbach's α 0.95 in Indianapolis and 0.83 in Ibadan). Scores on the CHIF correlated well with the Blessed Dementia scores at both sites (-0.71, p < 0.0001 for Indianapolis and -0.56, p < 0.0001 for Ibadan) and with the MMSE (0.75, p < 0.0001 for Indianapolis and 0.44, p < 0.0001 for Ibadan). For all items at both sites, the subjects without dementia performed significantly better than those with dementia. The area under the ROC curve for dementia diagnosis was 0.965 for Indianapolis and 0.925 for Ibadan. Conclusion: The CHIF is a useful instrument to assess function directly in elderly participants in international studies, particularly in the absence of reliable informants.

Original languageEnglish
Pages (from-to)653-666
Number of pages14
JournalInternational Psychogeriatrics
Volume18
Issue number4
DOIs
StatePublished - Dec 2006

Fingerprint

Dementia
Interviews
corticosteroid hormone-induced factor
antineoplaston A10
Activities of Daily Living
Reproducibility of Results
Sensitivity and Specificity

Keywords

  • ADL
  • African Americans
  • Dementia
  • IADL
  • Yoruba

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Aging
  • Psychiatry and Mental health
  • Psychology(all)
  • Clinical Psychology

Cite this

The development of a semi-structured home interview (CHIF) to directly assess function in cognitively impaired elderly people in two cultures. / Hendrie, Hugh; Lane, K. A.; Ogunniyi, A.; Baiyewu, O.; Gureje, O.; Evans, R.; Smith-Gamble, V.; Pettaway, M.; Unverzagt, Frederick; Gao, Sujuan; Hall, Kathleen.

In: International Psychogeriatrics, Vol. 18, No. 4, 12.2006, p. 653-666.

Research output: Contribution to journalArticle

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abstract = "Background: Assessing function is a crucial element in the diagnosis of dementia. This information is usually obtained from key informants. However, reliable informants are not always available. Methods: A 10-item semi-structured home interview (the CHIF, or Clinician Home-based Interview to assess Function) to assess function primarily by measuring instrumental activities of daily living directly was developed and tested for inter-rater reliability and validity as part of the Indianapolis-Ibadan dementia project. The primary validity measurements were correlations between scores on the CHIF and independently gathered scores on the Blessed Dementia Scale (from informants) and the Mini-mental State Examination (MMSE). Sensitivities and specificities of scores on the CHIF and receiver operator characteristic (ROC) curves were constructed with dementia as the dependent variable. Results: Inter-rater reliability for the CHIF was high (Pearson's correlation coefficient 0.99 in Indianapolis and 0.87 in Ibadan). Internal consistency, in both samples, was good (Cronbach's α 0.95 in Indianapolis and 0.83 in Ibadan). Scores on the CHIF correlated well with the Blessed Dementia scores at both sites (-0.71, p < 0.0001 for Indianapolis and -0.56, p < 0.0001 for Ibadan) and with the MMSE (0.75, p < 0.0001 for Indianapolis and 0.44, p < 0.0001 for Ibadan). For all items at both sites, the subjects without dementia performed significantly better than those with dementia. The area under the ROC curve for dementia diagnosis was 0.965 for Indianapolis and 0.925 for Ibadan. Conclusion: The CHIF is a useful instrument to assess function directly in elderly participants in international studies, particularly in the absence of reliable informants.",
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AU - Baiyewu, O.

AU - Gureje, O.

AU - Evans, R.

AU - Smith-Gamble, V.

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AU - Unverzagt, Frederick

AU - Gao, Sujuan

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