The development of callosal projections in normal and one-eyed rats

R. D. Lund, F. L.F. Chang, P. W. Land

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

The course of callosal development in area 17 of rats suggests that, unlike immediately adjacent regions, axons of callosal origin do not normally gain access to upper cortical layers, and this results in the loss of an early exuberant callosal pathway. Removal of optic input, however, permits invasion of these layers of area 17 by callosal axons and results in survival of callosally projecting neurons in area 17.

Original languageEnglish (US)
Pages (from-to)139-142
Number of pages4
JournalDevelopmental Brain Research
Volume14
Issue number1
DOIs
StatePublished - May 1984
Externally publishedYes

Keywords

  • axon ingrowth
  • axon pruning
  • corpus callosum
  • development
  • eye removal
  • plasticity

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Developmental Biology

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