The effect of exercise-training on sarcoplasmic reticulum function in fast and slow skeletal muscle

D. H. Kim, G. S. Wible, F. A. Witzmann, R. H. Fitts

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The effect of endurance exercise on the capacity of crube homogenates (CH) to sequester Ca2+ was determined in the slow type I soleus, the fast type IIA deep region of the vastus lateralis (DVL), and the fast type IIB superficial region of the vastus lateralis (SVL). The Ca2+ uptake capacity was affected by exercise in a fiber type specific manner. The fast-twitch SVL showed a 35% decrease in the maximal rate of Ca2+ uptake (Vmax) and a significantly lower Km while the slow soleus and fast DVL were unaltered. The time course of Ca2+ uptake, and the peak amount of Ca2+ sequestered was not altered by exercise in any of the muscles studied. The homogenates from the exercise-trained soleus muscles exhibited an increased ability to retain Ca2+ and in this capacity became more like fast muscle.

Original languageEnglish (US)
Pages (from-to)2671-2677
Number of pages7
JournalLife Sciences
Volume28
Issue number23
DOIs
StatePublished - Jun 8 1981

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Quadriceps Muscle
Sarcoplasmic Reticulum
Muscle
Skeletal Muscle
Exercise
Muscles
Durability
Fibers

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

The effect of exercise-training on sarcoplasmic reticulum function in fast and slow skeletal muscle. / Kim, D. H.; Wible, G. S.; Witzmann, F. A.; Fitts, R. H.

In: Life Sciences, Vol. 28, No. 23, 08.06.1981, p. 2671-2677.

Research output: Contribution to journalArticle

Kim, D. H. ; Wible, G. S. ; Witzmann, F. A. ; Fitts, R. H. / The effect of exercise-training on sarcoplasmic reticulum function in fast and slow skeletal muscle. In: Life Sciences. 1981 ; Vol. 28, No. 23. pp. 2671-2677.
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