The effect of high animal protein intake on the risk of calcium stone-formation in the urinary tract

W. G. Robertson, P. J. Heyburn, M. Peacock, F. A. Hanes, R. Swaminathan

Research output: Contribution to journalArticle

134 Scopus citations

Abstract

1. Studies were carried out on six normal male subjects to determine the short-term effect of increasing the dietary consumption of animal protein on the urinary risk factors for stone-formation, namely, volume, pH, calcium, oxalate, uric acid and glycosaminoglycans. 2. An increase of 34 g/day of animal protein in the diet significantly increased urinary calcium (23%) and oxalate (24%). Total urinary nitrogen increased by an average of 368 mmol/day. The accompanying increase in dietary purine (11 mmol of purine nitrogen/day) caused a 48% increase in the excretion of uric acid. 3. The overall relative probability of forming stones, calculated from a combination of the risk factors, was markedly increased (250%) throughout the period of high animal protein ingestion.

Original languageEnglish (US)
Pages (from-to)285-288
Number of pages4
JournalClinical Science
Volume57
Issue number3
DOIs
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Medicine(all)

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    Robertson, W. G., Heyburn, P. J., Peacock, M., Hanes, F. A., & Swaminathan, R. (1979). The effect of high animal protein intake on the risk of calcium stone-formation in the urinary tract. Clinical Science, 57(3), 285-288. https://doi.org/10.1042/cs0570285