The effect of lasalocid on Tl-201 biodistribution in the rat

Rita C. Gentilcore, Lynn R. Hendershott, Frederick S. Ordway, James W. Fletcher

Research output: Contribution to journalArticle


The effect of various concentrations of lasalocid on Tl-201 thallous chloride biodistribution in rats was investigated. Tl-201 activity increased in the blood and decreased in the heart and lungs in lasalocid treated rats. The effect of the lasalocid was dose-related. Partition coefficients were performed on lasalocid mixtures alone and in the presence of potassium. In the presence of lasalocid, an increased Tl-201 chloroformrwater partition coefficient was found, which was unaffected by the sequential addition of potassium in increasing concentrations.

Original languageEnglish (US)
Pages (from-to)307-311
Number of pages5
JournalNuclear Medicine Communications
Issue number5
StatePublished - Oct 1981

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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