The Effect of Simultaneous Administration of Levarterenol and Phentolamine on Renal Blood Flow

Vincent M. Cimmino, Edward L. Bove, Louis C. Argenta, John W. Brown, Marvin M. Kirsh

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The effect of simultaneous administration of levarterenol and phentolamine upon renal blood flow was studied over a 3-hour period in 22 mongrel dogs. The infusion of levarterenol alone produced a fall in renal blood flow that ranged from 28 to 58% from the baseline value. When both drugs were administered simultaneously, renal flow fell only 17 to 22% from baseline (p < 0.05). From these studies we conclude that the simultaneous administration of levarterenol and phentolamine in optimal ratios maintains renal blood flow near baseline levels.

Original languageEnglish (US)
Pages (from-to)158-163
Number of pages6
JournalAnnals of Thoracic Surgery
Volume21
Issue number2
DOIs
StatePublished - Jan 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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