The effectiveness of sealants in managing caries lesions

S. O. Griffin, E. Oong, W. Kohn, B. Vidakovic, B. F. Gooch, J. Bader, J. Clarkson, M. R. Fontana, D. M. Meyer, R. G. Rozier, J. A. Weintraub, Domenick Zero

Research output: Contribution to journalArticle

190 Citations (Scopus)

Abstract

A barrier to providing sealants is concern about inadvertently sealing over caries. This meta-analysis examined the effectiveness of sealants in preventing caries progression. We searched electronic databases for comparative studies examining caries progression in sealed permanent teeth. We used a random-effects model to estimate percentage reduction in the probability of caries progression in sealed vs. unsealed carious teeth. Six studies, including 4 randomized-controlled trials (RCT) judged to be of fair quality, were included in the analysis (384 persons, 840 teeth, and 1090 surfaces). The median annual percentage of non-cavitated lesions progressing was 2.6% for sealed and 12.6% for unsealed carious teeth. The summary prevented fraction for RCT was 71.3% (95%CI: 52.8%-82.5, no heterogeneity) up to 5 years after placement. Despite variation among studies in design and conduct, sensitivity analysis found the effect to be consistent in size and direction. Sealing non-cavitated caries in permanent teeth is effective in reducing caries progression.

Original languageEnglish (US)
Pages (from-to)169-174
Number of pages6
JournalJournal of Dental Research
Volume87
Issue number2
DOIs
StatePublished - Feb 2008

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Tooth
Randomized Controlled Trials
Meta-Analysis
Databases

Keywords

  • Caries
  • Pit and fissure sealants

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Griffin, S. O., Oong, E., Kohn, W., Vidakovic, B., Gooch, B. F., Bader, J., ... Zero, D. (2008). The effectiveness of sealants in managing caries lesions. Journal of Dental Research, 87(2), 169-174. https://doi.org/10.1177/154405910808700211

The effectiveness of sealants in managing caries lesions. / Griffin, S. O.; Oong, E.; Kohn, W.; Vidakovic, B.; Gooch, B. F.; Bader, J.; Clarkson, J.; Fontana, M. R.; Meyer, D. M.; Rozier, R. G.; Weintraub, J. A.; Zero, Domenick.

In: Journal of Dental Research, Vol. 87, No. 2, 02.2008, p. 169-174.

Research output: Contribution to journalArticle

Griffin, SO, Oong, E, Kohn, W, Vidakovic, B, Gooch, BF, Bader, J, Clarkson, J, Fontana, MR, Meyer, DM, Rozier, RG, Weintraub, JA & Zero, D 2008, 'The effectiveness of sealants in managing caries lesions', Journal of Dental Research, vol. 87, no. 2, pp. 169-174. https://doi.org/10.1177/154405910808700211
Griffin SO, Oong E, Kohn W, Vidakovic B, Gooch BF, Bader J et al. The effectiveness of sealants in managing caries lesions. Journal of Dental Research. 2008 Feb;87(2):169-174. https://doi.org/10.1177/154405910808700211
Griffin, S. O. ; Oong, E. ; Kohn, W. ; Vidakovic, B. ; Gooch, B. F. ; Bader, J. ; Clarkson, J. ; Fontana, M. R. ; Meyer, D. M. ; Rozier, R. G. ; Weintraub, J. A. ; Zero, Domenick. / The effectiveness of sealants in managing caries lesions. In: Journal of Dental Research. 2008 ; Vol. 87, No. 2. pp. 169-174.
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