Abstract
The cell-membrane folate receptor is a potential molecular target for tumor-selective drug delivery, including radiolabeled folate-chelate conjugates for diagnostic imaging. We review here some background on the folate receptor as tumor-associated molecular target for drug delivery, and briefly survey the literature on tumor-targeting with radiolabeled folate-chelate conjugates.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 811-817 |
| Number of pages | 7 |
| Journal | Nuclear Medicine and Biology |
| Volume | 30 |
| Issue number | 8 |
| DOIs | |
| State | Published - Nov 2003 |
| Externally published | Yes |
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Keywords
- Folate binding protein
- Folate receptor
- Radionuclide imaging
- Radiopharmaceutical
- Tumor targeting
ASJC Scopus subject areas
- Cancer Research
- Molecular Medicine
- Radiology Nuclear Medicine and imaging
Cite this
The folate receptor as a molecular target for tumor-selective radionuclide delivery. / Ke, Chun Yen; Mathias, Carla J.; Green, Mark.
In: Nuclear Medicine and Biology, Vol. 30, No. 8, 11.2003, p. 811-817.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The folate receptor as a molecular target for tumor-selective radionuclide delivery
AU - Ke, Chun Yen
AU - Mathias, Carla J.
AU - Green, Mark
PY - 2003/11
Y1 - 2003/11
N2 - The cell-membrane folate receptor is a potential molecular target for tumor-selective drug delivery, including radiolabeled folate-chelate conjugates for diagnostic imaging. We review here some background on the folate receptor as tumor-associated molecular target for drug delivery, and briefly survey the literature on tumor-targeting with radiolabeled folate-chelate conjugates.
AB - The cell-membrane folate receptor is a potential molecular target for tumor-selective drug delivery, including radiolabeled folate-chelate conjugates for diagnostic imaging. We review here some background on the folate receptor as tumor-associated molecular target for drug delivery, and briefly survey the literature on tumor-targeting with radiolabeled folate-chelate conjugates.
KW - Folate binding protein
KW - Folate receptor
KW - Radionuclide imaging
KW - Radiopharmaceutical
KW - Tumor targeting
UR - http://www.scopus.com/inward/record.url?scp=0347224284&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0347224284&partnerID=8YFLogxK
U2 - 10.1016/S0969-8051(03)00117-3
DO - 10.1016/S0969-8051(03)00117-3
M3 - Article
C2 - 14698784
AN - SCOPUS:0347224284
VL - 30
SP - 811
EP - 817
JO - Nuclear Medicine and Biology
JF - Nuclear Medicine and Biology
SN - 0969-8051
IS - 8
ER -