The frequency and significance of postintubation hypotension during emergency airway management

Alan C. Heffner, Douglas Swords, Jeffrey Kline, Alan E. Jones

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Objective: Arterial hypotension is a recognized complication of emergency intubation, but the consequence of this event is poorly described. Our aim was to identify the incidence of postintubation hypotension (PIH) after emergency intubation and to determine its association with inhospital mortality. Methods: Retrospective cohort study of tracheal intubations performed in a large, urban emergency department over a 1-year period. Patients were included if they were older than 17 years and had no systolic blood pressure measurements less than 90 mm Hg for 30 consecutive minutes before intubation. Patients were analyzed in 2 groups, those with PIH, defined as any recorded systolic blood pressure less than 90 mm Hg within 60 minutes of intubation, and those with no PIH. The primary outcome was inhospital mortality. Results: Of 465 patients who underwent emergency intubation, 336 met inclusion criteria and were analyzed. Postintubation hypotension occurred in 79 (23%) of 336 patients. Patients with PIH had significantly higher inhospital mortality (33% vs 21%; 95% confidence interval for 12% difference, 1%-23%) and longer mean intensive care length of stay (LOS) (9.7 vs 5.9 days, P <.01) and hospital LOS (17.0 vs 11.4 days, P <.01). Postintubation hypotension remained a significant predictor of inhospital mortality after adjusting for confounding using multivariable logistic regression analysis (odds ratio, 1.9; 95% confidence interval, 1.1-3.5). Conclusion: Postintubation hypotension occurs in almost one quarter of normotensive patients undergoing emergency intubation. Postintubation hypotension is independently associated with higher inhospital mortality and longer intensive care unit and hospital LOS.

Original languageEnglish (US)
JournalJournal of Critical Care
Volume27
Issue number4
DOIs
StatePublished - Aug 2012
Externally publishedYes

Fingerprint

Airway Management
Hypotension
Emergencies
Intubation
Hospital Mortality
Length of Stay
Blood Pressure
Confidence Intervals
Critical Care
Intensive Care Units
Hospital Emergency Service
Cohort Studies
Retrospective Studies
Logistic Models
Odds Ratio
Regression Analysis
Incidence

Keywords

  • Hypotension
  • Intubation
  • Mortality

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

The frequency and significance of postintubation hypotension during emergency airway management. / Heffner, Alan C.; Swords, Douglas; Kline, Jeffrey; Jones, Alan E.

In: Journal of Critical Care, Vol. 27, No. 4, 08.2012.

Research output: Contribution to journalArticle

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