The human metapneumovirus: A case series and review of the literature

Safi Shahda, W. G. Carlos, P. J. Kiel, B. A. Khan, C. A. Hage

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

Human metapneumovirus (hMPV) is an emerging human pulmonary pathogen that is genetically related to respiratory syncytial virus. It has been increasingly associated with respiratory illnesses over the last few decades. Immunocompromised patients are particularly susceptible with resultant morbidity and mortality. We describe our experience with 9 immunocompromised patients diagnosed with pneumonia secondary to hMPV, 2 of whom were successfully treated with aerosolized and oral ribavirin along with intravenous immunoglobulin (IVIG). We suggest that hMPV should be considered in the differential diagnosis of immunocompromised patients with acute respiratory illness. Ribavirin (oral and aerosolized) with IVIG is potentially an effective treatment option for those with severe disease.

Original languageEnglish (US)
Pages (from-to)324-328
Number of pages5
JournalTransplant Infectious Disease
Volume13
Issue number3
DOIs
StatePublished - Jun 1 2011

Keywords

  • Cellular rejection
  • Hematopoietic stem cell transplant
  • Human metapneumovirus
  • Immunosuppression
  • Lung transplant
  • Ribavirin

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

Fingerprint Dive into the research topics of 'The human metapneumovirus: A case series and review of the literature'. Together they form a unique fingerprint.

  • Cite this