The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches

Pankita H. Pandya, Mary E. Murray, Karen E. Pollok, Jamie L. Renbarger

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the fundamentals of incorporating precision medicine to discover new immune biomarkers and predictive signatures. Using a personalized approach may have a significant, positive impact on the use of oncolytics to better guide safer and more effective therapies.

Original languageEnglish (US)
Article number4273943
JournalJournal of Immunology Research
Volume2016
DOIs
StatePublished - 2016

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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