The impact of glaucoma medication on parameters of ocular perfusion

Alon Harris, Christian P. Jonescu-Cuypers

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Whereas intraocular pressure is considered a major risk factor in glaucoma, growing evidence now indicates that ocular ischemia plays a major role too. By virtue of this and because many existing medications are able to interact with vasculature, altering ocular blood flow, it is essential that current and future medications for glaucoma be evaluated for their effect on ocular circulation. The authors review published papers examining the effect of topical and some systemic medications on ocular blood flow, focusing mostly on data from the human eye. The authors provide a comprehensive review on the effect of subclasses of medications (eg, carbonic anhydrase inhibitors, β-blockers, α-adrenergic agonists, and prostaglandin analogues on optic nerve head, and on retinal, choroidal, and retrobulbar circulation. The various claims for enhancements or reduction of ocular circulation within each class of medication are reviewed and evaluated.

Original languageEnglish
Pages (from-to)131-137
Number of pages7
JournalCurrent Opinion in Ophthalmology
Volume12
Issue number2
DOIs
StatePublished - 2001

Fingerprint

Glaucoma
Perfusion
Carbonic Anhydrase Inhibitors
Synthetic Prostaglandins
Adrenergic Agonists
Optic Disk
Intraocular Pressure
Ischemia

ASJC Scopus subject areas

  • Ophthalmology

Cite this

The impact of glaucoma medication on parameters of ocular perfusion. / Harris, Alon; Jonescu-Cuypers, Christian P.

In: Current Opinion in Ophthalmology, Vol. 12, No. 2, 2001, p. 131-137.

Research output: Contribution to journalArticle

Harris, Alon ; Jonescu-Cuypers, Christian P. / The impact of glaucoma medication on parameters of ocular perfusion. In: Current Opinion in Ophthalmology. 2001 ; Vol. 12, No. 2. pp. 131-137.
@article{f170de2763124ea3ad3ea8b67730ab14,
title = "The impact of glaucoma medication on parameters of ocular perfusion",
abstract = "Whereas intraocular pressure is considered a major risk factor in glaucoma, growing evidence now indicates that ocular ischemia plays a major role too. By virtue of this and because many existing medications are able to interact with vasculature, altering ocular blood flow, it is essential that current and future medications for glaucoma be evaluated for their effect on ocular circulation. The authors review published papers examining the effect of topical and some systemic medications on ocular blood flow, focusing mostly on data from the human eye. The authors provide a comprehensive review on the effect of subclasses of medications (eg, carbonic anhydrase inhibitors, β-blockers, α-adrenergic agonists, and prostaglandin analogues on optic nerve head, and on retinal, choroidal, and retrobulbar circulation. The various claims for enhancements or reduction of ocular circulation within each class of medication are reviewed and evaluated.",
author = "Alon Harris and Jonescu-Cuypers, {Christian P.}",
year = "2001",
doi = "10.1097/00055735-200104000-00009",
language = "English",
volume = "12",
pages = "131--137",
journal = "Current Opinion in Ophthalmology",
issn = "1040-8738",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - The impact of glaucoma medication on parameters of ocular perfusion

AU - Harris, Alon

AU - Jonescu-Cuypers, Christian P.

PY - 2001

Y1 - 2001

N2 - Whereas intraocular pressure is considered a major risk factor in glaucoma, growing evidence now indicates that ocular ischemia plays a major role too. By virtue of this and because many existing medications are able to interact with vasculature, altering ocular blood flow, it is essential that current and future medications for glaucoma be evaluated for their effect on ocular circulation. The authors review published papers examining the effect of topical and some systemic medications on ocular blood flow, focusing mostly on data from the human eye. The authors provide a comprehensive review on the effect of subclasses of medications (eg, carbonic anhydrase inhibitors, β-blockers, α-adrenergic agonists, and prostaglandin analogues on optic nerve head, and on retinal, choroidal, and retrobulbar circulation. The various claims for enhancements or reduction of ocular circulation within each class of medication are reviewed and evaluated.

AB - Whereas intraocular pressure is considered a major risk factor in glaucoma, growing evidence now indicates that ocular ischemia plays a major role too. By virtue of this and because many existing medications are able to interact with vasculature, altering ocular blood flow, it is essential that current and future medications for glaucoma be evaluated for their effect on ocular circulation. The authors review published papers examining the effect of topical and some systemic medications on ocular blood flow, focusing mostly on data from the human eye. The authors provide a comprehensive review on the effect of subclasses of medications (eg, carbonic anhydrase inhibitors, β-blockers, α-adrenergic agonists, and prostaglandin analogues on optic nerve head, and on retinal, choroidal, and retrobulbar circulation. The various claims for enhancements or reduction of ocular circulation within each class of medication are reviewed and evaluated.

UR - http://www.scopus.com/inward/record.url?scp=0035083668&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035083668&partnerID=8YFLogxK

U2 - 10.1097/00055735-200104000-00009

DO - 10.1097/00055735-200104000-00009

M3 - Article

VL - 12

SP - 131

EP - 137

JO - Current Opinion in Ophthalmology

JF - Current Opinion in Ophthalmology

SN - 1040-8738

IS - 2

ER -