The importance of one-stage median sternotomy and retroperitoneal node dissection in disseminated testicular cancer

I. Mandelbaum, P. B. Yaw, Lawrence Einhorn, S. D. Williams, R. G. Rowland, J. P. Donohue

Research output: Contribution to journalArticle

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Abstract

More than 350 patients with testicular germ cell cancer have been treated with cisplatin combination chemotherapy. Seventy-two with metastases to the thorax who had operation are discussed here. In a subgroup of 24 patients with additional retroperitoneal disease, a one-stage median sternotomy was performed in 18 patients, and a thoracotomy in 6, with retroperitoneal node dissection. Seventeen patients had similar pathological lesions in the thorax and retroperitoneum; in 7, the lesions differed. There was no operative mortality in the entire group. Overall, chemotherapy altered the metastases to mature teratoma in 28 patients, and 27 are long-term survivors. Among 22 patients with fibrotic, necrotic masses, 19 are long-term survivors; 6 of the 22 with persistent carcinoma had chemotherapy postoperatively and are long-term survivors. The overall cure rate for patients with disseminated testicular cancer is approximately 80%. Among those who had a one-stage thoracoretroperitoneal procedure, long-term survival is 83%; for the entire thoracic surgical group, it is 74%.

Original languageEnglish
Pages (from-to)524-528
Number of pages5
JournalAnnals of Thoracic Surgery
Volume36
Issue number5
DOIs
StatePublished - 1983

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Sternotomy
Testicular Neoplasms
Dissection
Survivors
Thorax
Neoplasm Metastasis
Drug Therapy
Germ Cell and Embryonal Neoplasms
Teratoma
Thoracotomy
Combination Drug Therapy
Cisplatin
Carcinoma
Survival
Mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

The importance of one-stage median sternotomy and retroperitoneal node dissection in disseminated testicular cancer. / Mandelbaum, I.; Yaw, P. B.; Einhorn, Lawrence; Williams, S. D.; Rowland, R. G.; Donohue, J. P.

In: Annals of Thoracic Surgery, Vol. 36, No. 5, 1983, p. 524-528.

Research output: Contribution to journalArticle

Mandelbaum, I. ; Yaw, P. B. ; Einhorn, Lawrence ; Williams, S. D. ; Rowland, R. G. ; Donohue, J. P. / The importance of one-stage median sternotomy and retroperitoneal node dissection in disseminated testicular cancer. In: Annals of Thoracic Surgery. 1983 ; Vol. 36, No. 5. pp. 524-528.
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AU - Donohue, J. P.

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