The Importance of One-Stage Median Sternotomy and Retroperitoneal Node Dissection in Disseminated Testicular Cancer

Isidore Mandelbaum, Peter B. Yaw, Lawrence H. Einhorn, Stephen D. Williams, Randall G. Rowland, John P. Donohue

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

More than 350 patients with testicular germ cell cancer have been treated with cisplatin combination chemotherapy. Seventy-two with metastases to the thorax who had operation are discussed here. In a subgroup of 24 patients with additional retroperitoneal disease, a one-stage median sternotomy was performed in 18 patients, and a thoracotomy in 6, with retroperitoneal node dissection. Seventeen patients had similar pathological lesions in the thorax and retroperitoneum; in 7, the lesions differed. There was no operative mortality in the entire group. Overall, chemotherapy altered the metastases to mature teratoma in 28 patients, and 27 are long-term survivors. Among 22 patients with fibrotic, necrotic masses, 19 are long-term survivors; 6 of the 22 with persistent carcinoma had chemotherapy postoperatively and are long-term survivors. The overall cure rate for patients with disseminated testicular cancer is approximately 80%. Among those who had a one-stage thoracoretroperitoneal procedure, long-term survival is 83%; for the entire thoracic surgical group, it is 74%.

Original languageEnglish (US)
Pages (from-to)524-528
Number of pages5
JournalAnnals of Thoracic Surgery
Volume36
Issue number5
DOIs
StatePublished - Jan 1 1983

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ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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