The influence of body mass index on outcomes in ureteroscopy

Results from the clinical research office of endourological society URS global study

Amy Krambeck, Nienke Wijnstok, Peter Olbert, George Mitroi, Simon Bariol, Hemendra N. Shah, Ahmed S. El-Abd, Bulent Onal, Jean De La Rosette

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction: Although ureteroscopy (URS) has been established as a viable treatment for stones in obese patients, its safety and success has not been fully elucidated. The current study describes the worldwide prevalence of obesity in patients with urolithiasis and examines trends in URS outcomes, safety, and efficacy. Methods: This study utilized the Clinical Research Office of the Endourological Society (CROES) URS Global Study, which was a prospective, multicenter study including 11,885 patients treated with URS for urinary stones at 1 of 114 urology departments across 32 countries. The relationship between body mass index (BMI), diabetes, and creatinine, with retreatment, stone-free rates, complications, and long hospital stay, was examined with a multivariate logistic regression analyses. Results: Of the 10,099 URS patients with BMI data, 17.4% were obese and 2.2% were super obese. Overall, 86.7% patients were stone free and 16.8% required retreatment. Higher BMI was associated with lower stone-free rates, and any deviation from normal weight was associated with higher retreatment rates. In multivariate analysis controlling for several variables including stone size, the association between BMI and lower stone-free rates with higher retreatment rates persisted. Intraoperative complications occurred in 518 (5.1%) patients, and 343 (3.4%) experienced a postoperative complication. Postoperative complications were more frequent in the underweight and super obese subjects, and there was no relationship between BMI and intraoperative complications. Discussion: Although URS for stone disease was found to be an overall safe procedure for obese and super obese patients, efficacy of the procedure may be lower compared with normal-weight subjects and higher retreatment rates may be necessary.

Original languageEnglish (US)
Pages (from-to)20-26
Number of pages7
JournalJournal of Endourology
Volume31
Issue number1
DOIs
StatePublished - 2017
Externally publishedYes

Fingerprint

Ureteroscopy
Retreatment
Body Mass Index
Research
Intraoperative Complications
Weights and Measures
Urinary Calculi
Urolithiasis
Thinness
Urology
Patient Safety
Multicenter Studies
Length of Stay
Creatinine
Multivariate Analysis
Obesity
Logistic Models
Regression Analysis
Prospective Studies
Safety

Keywords

  • BMI
  • obesity
  • stone disease
  • URS

ASJC Scopus subject areas

  • Urology

Cite this

The influence of body mass index on outcomes in ureteroscopy : Results from the clinical research office of endourological society URS global study. / Krambeck, Amy; Wijnstok, Nienke; Olbert, Peter; Mitroi, George; Bariol, Simon; Shah, Hemendra N.; El-Abd, Ahmed S.; Onal, Bulent; De La Rosette, Jean.

In: Journal of Endourology, Vol. 31, No. 1, 2017, p. 20-26.

Research output: Contribution to journalArticle

Krambeck, Amy ; Wijnstok, Nienke ; Olbert, Peter ; Mitroi, George ; Bariol, Simon ; Shah, Hemendra N. ; El-Abd, Ahmed S. ; Onal, Bulent ; De La Rosette, Jean. / The influence of body mass index on outcomes in ureteroscopy : Results from the clinical research office of endourological society URS global study. In: Journal of Endourology. 2017 ; Vol. 31, No. 1. pp. 20-26.
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