The National Alzheimer's Coordinating Center (NACC) database: The uniform data set

Duane L. Beekly, Erin M. Ramos, William W. Lee, Woodrow D. Deitrich, Mary E. Jacka, Joylee Wu, Janene L. Hubbard, Thomas D. Koepsell, John C. Morris, Walter A. Kukull, Eric M. Reiman, Neil Kowall, Gary Landreth, Michael Shelanski, Kathleen Welsh-Bohmer, Allan I. Levey, Huntington Potter, Bernardino Ghetti, Donald Price, Bradley HymanRonald C. Petersen, Mary Sano, Steven H. Ferris, M. Marsel Mesulam, Jeffrey Kaye, David A. Bennett, Jerome Yesavage, Daniel Marson, Cornelia Beck, Charles DeCarli, Carl Cotman, Jeffrey L. Cummings, Leon J. Thal, William Markesbery, Sid Gilman, John Q. Trojanowski, Steven T. DeKosky, Helena Chui, Roger Rosenberg, Murray Raskind

Research output: Contribution to journalReview article

260 Scopus citations

Abstract

The National Alzheimer's Coordinating Center (NACC) is responsible for developing and maintaining a database of participant information collected from the 29 Alzheimer's Disease Centers (ADCs) funded by the National Institute on Aging (NIA). The NIA appointed the ADC Clinical Task Force to determine and define an expanded, standardized clinical data set, called the Uniform Data Set (UDS). The goal of the UDS is to provide ADC researchers a standard set of assessment procedures, collected longitudinally, to better characterize ADC participants with mild Alzheimer disease and mild cognitive impairment in comparison with nondemented controls. NACC implemented the UDS (September 2005) by developing data collection forms for initial and follow-up visits based on Clinical Task Force definitions, a relational database, and a data submission system accessible by all ADCs. The NIA requires ADCs to submit UDS data to NACC for all their Clinical Core participants. Thus, the NACC web site (https://www.alz.washington.edu) was enhanced to provide efficient and secure access data submission and retrieval systems.

Original languageEnglish (US)
Pages (from-to)249-258
Number of pages10
JournalAlzheimer disease and associated disorders
Volume21
Issue number3
DOIs
StatePublished - Jul 1 2007

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Keywords

  • Alzheimer disease
  • Data submission
  • Database
  • Dementia
  • NACC
  • UDS

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Neuroscience(all)

Cite this

Beekly, D. L., Ramos, E. M., Lee, W. W., Deitrich, W. D., Jacka, M. E., Wu, J., Hubbard, J. L., Koepsell, T. D., Morris, J. C., Kukull, W. A., Reiman, E. M., Kowall, N., Landreth, G., Shelanski, M., Welsh-Bohmer, K., Levey, A. I., Potter, H., Ghetti, B., Price, D., ... Raskind, M. (2007). The National Alzheimer's Coordinating Center (NACC) database: The uniform data set. Alzheimer disease and associated disorders, 21(3), 249-258. https://doi.org/10.1097/WAD.0b013e318142774e