The outcome of the HCC patients underwent ALPPS: Retrospective study

Chihan Peng, Chuan Li, Chang Liu, Tianfu Wen, Jiayin Yang, Bo Li, Lvnan Yan, Leonidas G. Koniaris

Research output: Contribution to journalArticle

Abstract

The complete resection offers the best long-term survival for advanced hepatocellular carcinoma patients. ALPPS as a choice of resection, how is its outcome compared to one-stage resection, liver transplantation and TACE? This retrospective study included 20 ALPPS patients. To minimize the effect of confounding influences of measured covariates, PSM was performed. The overall survival (OS), morbidity, mortality and the increasing rate, KGR were analyzed. The OS in ALPPS group is 27.4 (±3.8 months) moths and the TACE group is 13.5(±1.2 months) (P<.001), LT group is 41.3 (±3.2 months) (P=.048), Resection group is 31.8 (±2.6 months) (P=.368). And the medium increasing volume is 209.5 cm3 (±61.5 cm3) with the increasing ratio 52.4% (+26.9%). The ALPPS is a feasible treatment for HCC patients and it provides a better long-term survival than TACE and it is similar to Resection, less than LT.

Original languageEnglish (US)
Article numbere17182
JournalMedicine (United States)
Volume98
Issue number38
DOIs
StatePublished - Sep 1 2019

Keywords

  • ALPPS
  • TACE
  • overall survival
  • treatment

ASJC Scopus subject areas

  • Medicine(all)

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