The potential of translational bioinformatics approaches for pharmacology research

Lang Li

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The field of bioinformatics has allowed the interpretation of massive amounts of biological data, ushering in the era of 'omics' to biomedical research. Its potential impact on pharmacology research is enormous and it has shown some emerging successes. A full realization of this potential, however, requires standardized data annotation for large health record databases and molecular data resources. Improved standardization will further stimulate the development of system pharmacology models, using translational bioinformatics methods. This new translational bioinformatics paradigm is highly complementary to current pharmacological research fields, such as personalized medicine, pharmacoepidemiology and drug discovery. In this review, I illustrate the application of transformational bioinformatics to research in numerous pharmacology subdisciplines.

Original languageEnglish (US)
Pages (from-to)862-867
Number of pages6
JournalBritish Journal of Clinical Pharmacology
Volume80
Issue number4
DOIs
StatePublished - Oct 1 2015

    Fingerprint

Keywords

  • big data
  • clinical pharmacology
  • systems pharmacology
  • translational bioinformatics

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this